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Inhibition of TNFalpha-induced IkappaBalpha (unknown origin) degradation expressed in human HeLa cells at 50 uM pretreated 12.5 mins before TNFalpha addition measured after 30 mins by ELISA
Assay data:7 Tested
SummaryPubMed CitationRelated BioAssays by Target
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
SummaryPubMed Citation
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
Inhibition of IkappaBalpha phosphorylation in human MDA-MB-231 cells at 5 to 20 uM after 3 to 24 hrs by Western blot analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of IkappaBalpha phosphorylation in human MDA-MB-231 cells at 5 to 20 uM after 12 to 24 hrs by Western blot analysis
Inhibition of IkappaBalpha phosphorylation in human MDA-MB-231 cells after 12 hrs by Western blot analysis
Assay data:2 Tested
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
Summary
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Inhibition of TNFalpha-induced IkappaB-alpha phosphorylation in human K562/ADR cells assessed as decrease in NKkappaB activity at 0.3 uM measured at 12 to 48 hrs by Western blot analysis
Inhibition of TNF-alpha-induced IkappaBalpha phosphorylation in human A549 cells at 4 to 8 uM treated 4 hrs before TNFalpha stimulation measured after 30 mins by Western blotting
Inhibition of TNFalpha-induced IkappaBalpha (unknown origin) phosphorylation expressed in human HeLa cells pretreated 30 mins before TNFalpha addition measured up to 120 mins by ELISA in presence of proteasome inhibitor MG-132
Assay data:16 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
Inhibition of IkappaB-alpha degradation in TNF-alpha-stimulated human Jurkat cells at 40 uM preincubated for 2 hrs followed by TNF-alpha challenge measured after 2 to 90 mins by Western blot analysis
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
TLR-pathway-human_P2C ligand_TNF readout
Assay data:130 Active, 756 Tested
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
Inhibition of TNF-alpha-induced IkappaBalpha degradation in human A549 cells at 4 to 8 uM treated 4 hrs before TNFalpha stimulation measured after 30 mins by Western blotting
Inhibition of TNF-alpha-induced IkappaBalpha phosphorylation in human A549 cells at 100 uM incubated for 1 hr prior TNFalpha challenge measured after 15 mins by Western blot analysis in the presence of proteasome inhibitor MG-132
Assay data:3 Active, 4 Tested
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