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Phosphodiesterase PDE4 Eurofins Panlabs panel
Assay data:1 Tested
SummaryRelated BioAssays by Target
Panlabs assay PDE4A1A
Compound was evaluated for inhibition of human PDE4A in an in vitro cell free assay measured by time-resolved fluorescence resonance energy transfer method
Assay data:46 Active, 10 Activity ≤ 1 µM, 927 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of human recombinant PDE4A incubated for 30 mins by Scintillation Proximity Assay
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of human recombinant PDE4A
Assay data:4 Active, 1 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 4 Tested
Inhibition of human PDE4A
SummaryPubMed CitationRelated BioAssays by Target
Binding affinity to human PDE4 assessed as dissociation constant
Assay data:2 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested
Inhibition of human PDE4
Inhibition of PDE4A (unknown origin) using cAMP as substrate incubated for 30 mins by Ba(OH)2 precipitation assay based scintillation counter
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of PDE4 (unknown origin)
Assay data:3 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 3 Tested
Inhibition of human PDE4 assessed as inhibition constant
Selectivity interaction (PDE panel (enzymatic activity assay)) EUB0000751a PDE4A
Assay data:1 Active, 1 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Selectivity interaction (PDE panel (enzymatic assay)) EUB0000744a PDE4A
Inhibition of PDE4A (unknown origin) at 1 to 10 uM by fluorescence polarization based assay
Assay data:2 Tested
Inhibition of human PDE4 expressed in Sf9 cells by non-linear regression analysis
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of cAMP-specific 3',5'-cyclic phosphodiesterase (unknown origin)
Assay data:2 Active, 1 Activity ≤ 1 µM, 4 Tested
Inhibition of human PDE4 at 10 uM measured by radioligand binding assay relative to control
Inhibition of human PDE4 at 10 uM relative to control
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