BioAssay by Target (List) for Gene (Select 5144) - PubChem BioAssay - NCBI

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Select item 19630841.

Safety47 Scan (DiscoverX - Eurofins)

Source:: ChEMBL

Protein Target:: cAMP-specific 3',5'-cyclic phosphodiesterase 4D

Assay data:1 Tested

AID:: 1963084

Summary Related BioAssays by Target

Select item 19624972.

Phosphodiesterase PDE4 Eurofins Panlabs panel

Source:: ChEMBL

Protein Targets:: cAMP-specific 3',5'-cyclic phosphodiesterase 4A; ...
Total:: 4

Assay data:1 Tested

AID:: 1962497

Summary Related BioAssays by Target

Select item 19624733.

Panlabs assay PDE4D2

Source:: ChEMBL

Protein Target:: cAMP-specific 3',5'-cyclic phosphodiesterase 4D

Assay data:1 Tested

AID:: 1962473

Summary Related BioAssays by Target

Select item 19623974.

PDE4D2 Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: cAMP-specific 3',5'-cyclic phosphodiesterase 4D

Assay data:1 Tested

AID:: 1962397

Summary Related BioAssays by Target

Select item 19623485.

PDE4D2 Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: cAMP-specific 3',5'-cyclic phosphodiesterase 4D

Assay data:1 Tested

AID:: 1962348

Summary Related BioAssays by Target

Select item 19622506.

PDE4D2 Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: cAMP-specific 3',5'-cyclic phosphodiesterase 4D

Assay data:1 Tested

AID:: 1962250

Summary Related BioAssays by Target

Select item 19622037.

PDE4D2 Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: cAMP-specific 3',5'-cyclic phosphodiesterase 4D

Assay data:1 Tested

AID:: 1962203

Summary Related BioAssays by Target

Select item 19621388.

PDE4D2 Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: cAMP-specific 3',5'-cyclic phosphodiesterase 4D

Assay data:1 Tested

AID:: 1962138

Summary Related BioAssays by Target

Select item 19621079.

PDE4D2 Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: cAMP-specific 3',5'-cyclic phosphodiesterase 4D

Assay data:1 Tested

AID:: 1962107

Summary Related BioAssays by Target

Select item 196206310.

PDE4D2 Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: cAMP-specific 3',5'-cyclic phosphodiesterase 4D

Assay data:1 Tested

AID:: 1962063

Summary Related BioAssays by Target

Select item 196181511.

Compound was evaluated for inhibition of human PDE4D in an in vitro cell free assay measured by scintillation proximity assay

Source:: ChEMBL

Protein Target:: cAMP-specific 3',5'-cyclic phosphodiesterase 4D

Assay data:109 Active, 1 Activity ≤ 1 nM, 13 Activity ≤ 1 µM, 1242 Tested

AID:: 1961815

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 193410312.

Inhibition of human recombinant PDE4D incubated for 30 mins by Scintillation Proximity Assay

Source:: ChEMBL

Protein Target:: cAMP-specific 3',5'-cyclic phosphodiesterase 4D

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1934103

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 193326813.

Inhibition of human recombinant PDE4D

Source:: ChEMBL

Protein Target:: cAMP-specific 3',5'-cyclic phosphodiesterase 4D

Assay data:4 Active, 1 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 4 Tested

AID:: 1933268

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 192445414.

Binding affinity to human PDE4 assessed as dissociation constant

Source:: ChEMBL

Protein Targets:: cAMP-specific 3',5'-cyclic phosphodiesterase 4A; ...
Total:: 4

Assay data:2 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1924454

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 192445315.

Inhibition of human PDE4D3

Source:: ChEMBL

Protein Target:: cAMP-specific 3',5'-cyclic phosphodiesterase 4D

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1924453

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 192445216.

Inhibition of human PDE4D7

Source:: ChEMBL

Protein Target:: cAMP-specific 3',5'-cyclic phosphodiesterase 4D

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1924452

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 192444917.

Inhibition of human PDE4

Source:: ChEMBL

Protein Targets:: cAMP-specific 3',5'-cyclic phosphodiesterase 4A; ...
Total:: 4

Assay data:1 Tested

AID:: 1924449

Summary PubMed Citation Related BioAssays by Target

Select item 192356418.

Inhibition of human C-terminal 6His-tagged PDE4D3 using cAMP as substrate

Source:: ChEMBL

Protein Target:: cAMP-specific 3',5'-cyclic phosphodiesterase 4D

Assay data:1 Active, 2 Tested

AID:: 1923564

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 192356319.

Inhibition of human C-terminal 6His-tagged PDE4D catalytic domain using cAMP as substrate

Source:: ChEMBL

Protein Target:: cAMP-specific 3',5'-cyclic phosphodiesterase 4D

Assay data:2 Tested

AID:: 1923563

Summary PubMed Citation Related BioAssays by Target

Select item 192356120.

Displacement of [3H]-cAMP from full-length recombinant human PDE4D7 by fluorescence polarisation assay

Source:: ChEMBL

Protein Target:: cAMP-specific 3',5'-cyclic phosphodiesterase 4D

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1923561

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

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Target

Proteins (1)
BioAssays with protein sequences specified as targets
RNAi Target, Active (6)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (447)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (96)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (362)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (501)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (9)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (725)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (13)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (699)
BioAssays extracted from the literature
NIH MLP (1)
BioAssays deposited by the NIH Molecular Libraries Program
Other (38)
BioAssays deposited by other experimentalists

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