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Inhibition of CLK4 (unknown origin)
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of recombinant human CLK4 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scintillation counter analysis
Assay data:45 Active, 40 Activity ≤ 1 µM, 56 Tested
Inhibition of human CLK4
Assay data:16 Active, 16 Activity ≤ 1 µM, 16 Tested
Inhibition of human CLK4 at 12 degree celcius
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of human CLK4 administered orally
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of CLK1/2/4 (unknown origin) relative to control
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Selectivity interaction (KinomeScan (DiscoverX)) EUB0000348aPTSA CLK4
SummaryRelated BioAssays by Target
Selectivity interaction (KinomeScan (DiscoverX)) EUB0000347a CLK4
Selectivity interaction (ScanMAX (DiscoverX)) EUB0000298b CLK4
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Selectivity interaction (SelectScreen (Invitrogen)) EUB0000715a CLK4
Selectivity interaction (KinomeScan (DiscoverX)) EUB0000702a CLK4
Affinity Biochemical interaction (NanoBRET assay (in HEK293T cells)) EUB0000009b CLK4
Affinity On-target Cellular interaction (NanoBRET assay (HEK293T cells)) EUB0000724a CLK4
Affinity On-target Cellular interaction (MTT assay (cellular toxicity in MCF-7, MCF-10a and MDA-MB-231 cells, 24h)) EUB0000009b CLK4
Affinity On-target Cellular interaction (NanoBRET assay (HEK293T cells)) EUB0000705a CLK4
Affinity On-target Cellular interaction (NanoBRET assay (HEK293T cells)) EUB0000321b CLK4
Assay data:1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, activity ≤ 1 µMRelated BioAssays by Target
Affinity Phenotypic Cellular interaction (Changed alternative splicing pattern determined by mRNAseq) EUB0000321b CLK4
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
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