BioAssay by Target (List) for Gene (Select 5837) - PubChem BioAssay - NCBI

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Select item 15085881.

RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen

Source:: Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre

Assay data:790 Active, 18119 Tested

AID:: 1508588

Select item 12248302.

Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout

Source:: Iain Fraser

Assay data:2853 Active, 18113 Tested

AID:: 1224830

Summary Related BioAssays by Same Project

Select item 11867383.

Inhibition of glycogen phosphorylase b (unknown origin)

Source:: ChEMBL

Protein Target:: Glycogen phosphorylase, muscle form

Assay data:1 Active, 1 Activity ≤ 1 µM, 3 Tested

AID:: 1186738

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 11595844.

A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line

Source:: Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre

Assay data:2442 Active, 18052 Tested

AID:: 1159584

Summary PubMed Citation

Select item 11595785.

A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen

Source:: Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre

Assay data:1034 Active, 18120 Tested

AID:: 1159578

Summary Related BioAssays by Depositor

Select item 11595066.

Identification of proteins required for the processing of the EWS-FLI1 nascent transcript

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:59220 Tested

AID:: 1159506

Select item 11173577.

InfectX: Pathogen infection siRNA screens

Source:: InfectX Consortium

Assay data:115372 Tested

AID:: 1117357

Summary PubMed Citation

Select item 11172818.

A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:555 Active, 64752 Tested

AID:: 1117281

Summary PubMed Citation

Select item 7434549.

RNAi screen for vorinostat resistance genes - Primary Screen

Source:: Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre

Assay data:450 Active, 18118 Tested

AID:: 743454

Summary PubMed Citation

Select item 74312110.

Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:167 Active, 26449 Tested

AID:: 743121

Select item 66742611.

Inhibition of glycogen phosphorylase b

Source:: ChEMBL

Protein Target:: Glycogen phosphorylase, muscle form

Assay data:3 Active, 3 Tested

AID:: 667426

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 66742312.

Inhibition of glycogen phosphorylase b in human HepG2 cells after 3 hrs

Source:: ChEMBL

Protein Target:: Glycogen phosphorylase, muscle form

Assay data:1 Tested

AID:: 667423

Summary PubMed Citation Related BioAssays by Target

Select item 65181113.

Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:9227 Active, 64752 Tested

AID:: 651811

Summary PubMed Citation

Select item 65181014.

Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:826 Active, 18119 Tested

AID:: 651810

Summary PubMed Citation

Select item 62409915.

An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes

Source:: ICCB-Longwood Screening Facility, Harvard Medical School

Assay data:497 Active, 21019 Tested

AID:: 624099

Summary PubMed Citation

Select item 53759916.

Inhibition of glycogen phosphorylase b

Source:: ChEMBL

Protein Target:: Glycogen phosphorylase, muscle form

Assay data:1 Active, 1 Tested

AID:: 537599

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 25490517.

Inhibitory concentration against glycogen phosphorylase of rabbit muscle

Source:: ChEMBL

Protein Target:: Glycogen phosphorylase, muscle form

Assay data:22 Active, 17 Activity ≤ 1 µM, 27 Tested

AID:: 254905

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 25489318.

Inhibitory concentration against rabbit muscle glycogen phosphorylase

Source:: ChEMBL

Protein Target:: Glycogen phosphorylase, muscle form

Assay data:3 Tested

AID:: 254893

Summary PubMed Citation Related BioAssays by Target

Select item 22701419.

Ratio of HMGP to that of HLGP was determined

Source:: ChEMBL

Protein Target:: Glycogen phosphorylase, muscle form

Assay data:17 Tested

AID:: 227014

Summary PubMed Citation Related BioAssays by Target

Select item 14123320.

Inhibitor constant was measured against Muscle phosphorylase b in rabbit

Source:: ChEMBL

Protein Target:: Glycogen phosphorylase, muscle form

Assay data:2 Active, 2 Tested

AID:: 141233

Summary Compounds, Active PubMed Citation Related BioAssays by Target

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Target

RNAi Target, Active (6)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (11)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 µM (7)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (15)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (9)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (18)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (13)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (18)
BioAssays extracted from the literature
NIH MLP (1)
BioAssays deposited by the NIH Molecular Libraries Program
Other (12)
BioAssays deposited by other experimentalists

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