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Agonist activity at GPR39 in primary gastric mucosal cells isolated from C57BL/6 mouse assessed as myo-[2-3H]inositol phosphate accumulation in presence of 10 uM Zn2+ measured after 75 mins by scintillation proximity assay
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Agonist activity at GPR39 in primary gastric mucosal cells isolated from C57BL/6 mouse assessed as inhibition of isoproterenol-induced ghrelin secretion at 1 uM in presence of 10 uM of Zn2+ and somatostatin receptor antagonist BIM-23627 measured after 4 hrs by ELISA
Agonist activity at GPR39 in primary gastric mucosal cells isolated from C57BL/6 mouse assessed as inhibition of isoproterenol-induced ghrelin secretion at 1 uM in presence of 10 uM of Zn2+ measured after 4 hrs by ELISA relative to basal level
Agonist activity at mouse GPR39 expressed in HEK293 cells co-expressing Galphaq assessed as myo-[2-3H]inositol phosphate accumulation in presence of 10 uM Zn2+ measured after 75 mins by scintillation proximity assay
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Agonist activity at mouse GPR39 expressed in HEK293 cells co-expressing Galphaq assessed as myo-[2-3H]inositol phosphate accumulation measured after 75 mins by scintillation proximity assay
Agonist activity at mouse GPR39 expressed in HEK293 cells by IP1 assay
Assay data:20 Active, 2 Activity ≤ 1 nM, 15 Activity ≤ 1 µM, 22 Tested
Agonist activity at mouse GPR39 by IP1 assay
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