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Inhibition of human NTPDase-2 expressed in CHO-K1 cells in presence of DNA/LTX mixture
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of human NTPDase 2 expressed in human COS7 cells using ATP as substrate at 50 uM incubated for 5 mins followed by substrate addition and measured after 30 mins by capillary electrophoresis method
Inhibition of human NTPDase2 expressed in green monkey Cos-7 cells using ATP as substrate preincubated for 3 mins followed by substrate addition by malachite green reagent based assay
Assay data:1 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of NTPDase 2 (unknown origin) expressed in CHO cells using ATP as substrate preincubated for 1 hr followed by substrate addition and measured after 50 mins by PiColorLock gold reagent based colorimetric assay
Assay data:3 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of human NTPDase 2 expressed in CHO cells using ATP as substrate preincubated for 1 hr followed by substrate addition and measured after 50 mins by colorimetric assay
Inhibition of human NTPdase-2 expressed in COS7 cell membranes at 100 uM using ATP as substrate preincubated for 3 mins followed by susbtrate addition and measured after 10 mins by malachite green dye based method
Assay data:4 Active, 6 Tested
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Inhibition of human NTPDase2 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed by substrate addition measured after 10 mins by malachite green reagent-based assay
Assay data:14 Tested
Activation of human NTPDase2 using ATP as substrate preincubated for 3 mins followed by substrate addition measured after 10 mins by malachite green reagent-based assay relative to control
Drug metabolism assessed as human NTPDase2-mediated compound hydrolysis at 100 uM relative to ATP
Assay data:4 Tested
Inhibition of human NTPDase2 at 100 uM using ATP as substrate preincubated for 3 mins followed by substrate addition measured after 10 mins by malachite green reagent-based assay
Assay data:3 Tested
Human ectonucleoside triphosphate diphosphohydrolase 2 (Hydrolases)
Assay data:1 Active, 1 Tested
Inhibition of recombinant human NTPDase2 expressed in CHO cells using ADP as substrate incubated for 10 mins by capillary electrophoresis method
Inhibition of human recombinant NTPDase2 expressed in CHO cells using ATP as substrate at 10 to 1000 uM preincubated with substrate followed by protein addition and subsequent incubation for 30 mins by capillary electrophoresis
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
Inhibition of recombinant human NTPDase2 transfected in COS-7 cells using ATP substrate
Inhibition of recombinant human NTPDase2 transfected in COS-7 cells using ATP substrate at 100 uM relative to control
Assay data:7 Tested
Stability assessed as human NTPDase2-mediated compound hydrolysis
Assay data:9 Tested
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
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