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Human ADAM17 (M12: Astacin/Adamalysin)
Assay data:5 Active, 5 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Summary of the probe development effort to identify exosite inhibitors of ADAM17.
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Late stage QFRET-based biochemical high throughput dose response assay to identify exosite inhibitors of ADAM17
Assay data:2 Active, 24 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
QFRET-based biochemical high throughput dose response assay to identify exosite inhibitors of ADAM17
Assay data:5 Active, 1 Activity ≤ 1 µM, 248 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Counterscreen for exosite inhibitors of ADAM17: Fluorescence resonance energy transfer (FRET)-based biochemical high throughput dose response assay to identify inhibitors of ADAM10
Assay data:28 Active, 1 Activity ≤ 1 µM, 248 Tested
Counterscreen for exosite inhibitors of ADAM10: QFRET-based biochemical high throughput dose response assay to identify inhibitors of ADAM17
Assay data:3 Active, 1 Activity ≤ 1 µM, 235 Tested
QFRET-based biochemical high throughput confirmation assay to identify exosite inhibitors of ADAM17
Assay data:1855 Active, 2872 Tested
Counterscreen for exosite inhibitors of ADAM17: Fluorescence resonance energy transfer (FRET)-based biochemical high throughput screening assay to identify inhibitors of ADAM10
Assay data:1336 Active, 2872 Tested
Counterscreen for exosite inhibitors of ADAM10: QFRET-based biochemical high throughput screening assay to identify inhibitors of ADAM17
Assay data:10 Active, 2125 Tested
QFRET-based biochemical primary high throughput screening assay to identify exosite inhibitors of ADAM17.
Assay data:3080 Active, 370276 Tested
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