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GENE-TOX mutagenicity studies
Assay data:1995 Active, 3214 Tested
SummaryCompounds, Active
CCRIS mutagenicity studies
Assay data:4929 Active, 8266 Tested
qHTS assay to identify small molecule agonists of the estrogen related receptor (ERR) signaling pathway from Tox21 library: Summary
Assay data:309 Active, 9667 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS assay to identify small molecule agonists of the estrogen related receptor signaling pathway with the pleiotropic PPARgamma coactivator (PGC) from Tox21 10K library: Summary
Assay data:390 Active, 9667 Tested
qHTS assay to identify small molecule antagonists of the estrogen receptor beta (ER-beta) signaling pathway: Summary
Assay data:593 Active, 9667 Tested
qHTS assay to identify small molecule agonists of the sonic hedgehog signaling (Shh) pathway: Summary
Assay data:45 Active, 9667 Tested
qHTS assay to identify small molecule agonists of the estrogen receptor beta (ER-beta) signaling pathway - cell viability counter screen
Assay data:1136 Active, 121 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same Project
qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line in the presence of 0.1 nM 17-beta-estradiol: Summary
Assay data:581 Active, 153 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Displacement of [3H]CGP54626 from GABA-B receptor (unknown origin) by radioligand binding assay
Assay data:1 Active, 3 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Displacement of [3H]baclofen from GABA-B receptor in cat cerebellum
Assay data:3 Active, 2 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Antagonist activity against beta-1 adrenergic receptor (unknown origin)
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
qHTS assay to identify small molecule agonists of the constitutive androstane receptor (CAR) signaling pathway: Summary
Assay data:1090 Active, 9667 Tested
qHTS assay to identify small molecule agonists of the estrogen related receptor (ERR) signaling pathway from Tox21 library
Assay data:318 Active, 199 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule agonists of the hypoxia (HIF-1) signaling pathway - cell viability counter screen
Assay data:617 Active, 94 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule agonists of the thyroid stimulating hormone receptor (TSHR) signaling pathway
Assay data:320 Active, 42 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule agonists of the estrogen related receptor signaling pathway with the pleiotropic PPARgamma coactivator (PGC) from Tox21 10K library
Assay data:323 Active, 134 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule agonists of the constitutive androstane receptor (CAR) signaling pathway
Assay data:853 Active, 48 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule inhibitors of firefly luciferase
Assay data:866 Active, 28 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule agonists of the estrogen related receptor (ERR) signaling pathway
Assay data:40 Active, 25 Activity ≤ 1 µM, 1366 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Inhibition of human recombinant CYP2J2 assessed as reduction in astemizole O-demethylation by LC-MS/MS method
Assay data:12 Active, 3 Activity ≤ 1 µM, 69 Tested
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