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2143 Elucidating the Mechanism of Action of a Novel Probe that Upregulates TRIB1 Expression and Modulates LDL Metabolism in Hepatic Cells
SummaryRelated BioAssays by DepositorRelated BioAssays by Same Project
Cholesterol depletion effects on gene expression Measured in Cell-Based System Using RT-PCR - 2143-13_Activator_Dose_CherryPick_Activity
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
Elucidating the Mechanism of Action of a Novel Probe that Upregulates TRIB1 Expression and Modulates LDL Metabolism in Hepatic Cells Measured in Cell-Based System Using RT-PCR - 2143-02_Activator_Dose_CherryPick_Activity
Assay data:2 Active, 2 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Same Project
qPCR Assay Determining Trib1 mRNA Expression 2143-01_Activator_Dose_Activity
Assay data:2 Active, 3 Tested
HepG2 Viability Measured in Cell-Based System Using Plate Readehe Mechanism of Action of a Novel Probr - 2143-05_Activator_Dose_CherryPick_Activity
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
LDL Uptake Measured in Cell-Based System Using Imaging - 2143-09_Activator_Dose_CherryPick_Activity
LDL Uptake Measured in Cell-Based System Using Imaging - 2143-09_Activator_Dose_CherryPick_Activity_Set2
ERK1/2 phosphorylation in HepG2 cells with Trib1 inducers Measured in Cell-Based System Using Imaging - 2143-14_Activator_Dose_CherryPick_Activity
PCSK9 ELISA Measured in Cell-Based System Using Plate Reader - 2143-17_Activator_Dose_CherryPick_Activity
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same Project
Quantification of triglyceride synthesis as measured by LC-MS Measured in Biochemical System- 2143-12_Activator_Dose_CherryPick_Activity
ApoB ELISA Measured in Cell-Based System Using Plate Reader - 2143-16_Activator_Dose_CherryPick_Activity
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
Effects MEK inhibition Measured in Cell-Based System Using RT-PCR - 2143-18_Activator_Dose_CherryPick_Activity
Effects of statins on PCSK9 Measured in Cell-Based System Using RT-PCR - 2143-15_Activator_Dose_CherryPick_Activity
Effects of statins on LDLR Measured in Cell-Based System Using RT-PCR - 2143-22_Activator_Dose_CherryPick_Activity
LDLR ELISA Measured in Cell-Based System Using Plate Reader - 2143-23_Activator_Dose_CherryPick_Activity
Effects of JAK inhibition Measured in Cell-Based System Using RT-PCR - 2143-19_Activator_Dose_CherryPick_Activity
Target deconvolution using SILAC Measured in Biochemical System- 2143-27_Activator_Dose_CherryPick_Activity
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qPCR Trib1 Timecourse Measured in Cell-Based System Using RT-PCR - 2143-26_Activator_Dose_CherryPick_ActivityqPCR Trib1 Timecourse Measured in Cell-Based System Using RT-PCR - 2143-26_Activator_Dose_CherryPick_Activity
qPCR PCSK9 Timecourse Measured in Cell-Based System Using RT-PCR - 2143-25_Activator_Dose_CherryPick_Activity
qPCR LDLR Timecourse Measured in Cell-Based System Using RT-PCR - 2143-24_Activator_Dose_CherryPick_Activity
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