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Quantitative High-Throughput Screen for Enhancers of SMN2 Splice Variant Expression: Summary
Assay data:17 Active, 38 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Counterscreen Assay for Enhancers of SMN2 Splice Variant Expression: Modulation of SMN1 Expression for Further Probe SAR
Assay data:30 Active, 7 Activity ≤ 1 µM, 134 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS Assay for Enhancers of SMN2 Splice Variant Expression
Assay data:5854 Active, 11 Activity ≤ 1 nM, 5217 Activity ≤ 1 µM, 211511 Tested
Counterscreen Assay for Enhancers of SMN2 Splice Variant Expression: Interaction with Luciferase Reporter
Assay data:16 Active, 4 Activity ≤ 1 µM, 81 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same Project
Counterscreen Assay for Enhancers of SMN2 Splice Variant Expression: Modulation of SMN1 Expression
Assay data:13 Active, 88 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Confirmation Concentration-Response Assay for Enhancers of SMN2 Splice Variant Expression
Assay data:8 Active, 10 Activity ≤ 1 µM, 88 Tested
Counterscreen Assay for Enhancers of SMN2 Splice Variant Expression: Modulation of SMN1 Expression for Probe SAR
Assay data:1 Active, 29 Tested
Confirmation Concentration-Response Assay for Enhancers of SMN2 Splice Variant Expression for Probe SAR
Assay data:16 Active, 5 Activity ≤ 1 µM, 29 Tested
Counterscreen Assay for Enhancers of SMN2 Splice Variant Expression: Interaction with Luciferase Reporter for Probe SAR
Assay data:10 Active, 28 Tested
Extended Characterization of SMN2 Inhibitors: Righting Time Studies
Assay data:1 Active, 1 Tested
Confirmation Concentration-Response Assay for Enhancers of SMN2 Splice Variant Expression for Further Probe SAR
Assay data:78 Active, 32 Activity ≤ 1 µM, 134 Tested
Counterscreen Assay for Enhancers of SMN2 Splice Variant Expression: Interaction with Luciferase Reporter for Further Probe SAR
Assay data:41 Active, 5 Activity ≤ 1 µM, 134 Tested
Enhancers of SMN2 Splice Variant Expression: Metabolic Stability in presence of NADPH Profiling
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
Enhancers of SMN2 Splice Variant Expression: Metabolic Stability in absence of NADPH Profiling
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
Enhancers of SMN2 Splice Variant Expression: Caco-2 Permeability Profiling
Enhancers of SMN2 Splice Variant Expression: Efflux Ratio Profiling
Extended Characterization of SMN2 Inhibitors: Survival Studies
Extended Characterization of SMN2 Inhibitors: Body Weight Studies
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