Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Agonist activity at FXR in guggulsterone-treated human LO2 cells assessed as reduction in NTCP protein expression at 80 uM treated with FXR antagonist, guggulsterone for 24 hrs followed by incubation with compound for 24 hrs by western blot analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Agonist activity at FXR in guggulsterone-treated human LO2 cells assessed as reduction in CYP8B1 protein expression at 80 uM treated with FXR antagonist, guggulsterone for 24 hrs followed by incubation with compound for 24 hrs by western blot analysis
Agonist activity at FXR in guggulsterone-treated human LO2 cells assessed as reduction in CYP7A1 protein expression at 80 uM treated with FXR antagonist, guggulsterone for 24 hrs followed by incubation with compound for 24 hrs by western blot analysis
Agonist activity at FXR in guggulsterone-treated human LO2 cells assessed as increase in SULT2A1 protein expression at 80 uM treated with FXR antagonist, guggulsterone for 24 hrs followed by incubation with compound for 24 hrs by western blot analysis
Agonist activity at FXR in guggulsterone-treated human LO2 cells assessed as increase in MRP2 protein expression at 80 uM treated with FXR antagonist, guggulsterone for 24 hrs followed by incubation with compound for 24 hrs by western blot analysis
Agonist activity at FXR in guggulsterone-treated human LO2 cells assessed as increase in BSEP protein expression at 80 uM treated with FXR antagonist, guggulsterone for 24 hrs followed by incubation with compound for 24 hrs by western blot analysis
Agonist activity at FXR in guggulsterone-treated human LO2 cells assessed as increase in SHP1 protein expression at 80 uM treated with FXR antagonist, guggulsterone for 24 hrs followed by incubation with compound for 24 hrs by western blot analysis
Increase in FXR protein expression in guggulsterone-treated human LO2 cells at 80 uM treated with FXR antagonist, guggulsterone for 24 hrs followed by incubation with compound for 24 hrs by western blot analysis
SummaryCompounds, ActivePubMed Citation
Agonist activity at FXR in human LO2 cells assessed as decrease in NTCP protein expression at 0.25 uM after 24 hrs by Western blot analysis
Agonist activity at FXR in human LO2 cells assessed as decrease in CYP8B1 protein expression at 0.25 uM after 24 hrs by Western blot analysis
Agonist activity at FXR in human LO2 cells assessed as decrease in CYP7A1 protein expression at 0.25 uM after 24 hrs by Western blot analysis
Agonist activity at FXR in human LO2 cells assessed as increase in SULT2A protein expression at 0.25 uM after 24 hrs by Western blot analysis
Agonist activity at FXR in human LO2 cells assessed as increase in MRP2 protein expression at 0.25 uM after 24 hrs by Western blot analysis
Agonist activity at FXR in human LO2 cells assessed as increase in BSEP protein expression at 0.25 uM after 24 hrs by Western blot analysis
Agonist activity at FXR in human LO2 cells assessed as increase in SHP1 protein expression at 0.25 uM after 24 hrs by Western blot analysis
Upregulation of FXR protein expression in human LO2 cells at 0.25 uM after 24 hrs by Western blot analysis
Agonist activity at FXR in human LO2 cells assessed as decrease in NTCP protein expression at 80 uM after 24 hrs by Western blot analysis
Agonist activity at FXR in human LO2 cells assessed as decrease in CYP8B1 protein expression at 80 uM after 24 hrs by Western blot analysis
Agonist activity at FXR in human LO2 cells assessed as decrease in CYP7A1 protein expression at 80 uM after 24 hrs by Western blot analysis
Agonist activity at FXR in human LO2 cells assessed as increase in SULT2A protein expression at 80 uM after 24 hrs by Western blot analysis
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on