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Binding affinity to human IPO5 in human PC-3 cell lysate assessed as inhibition of IPO5 interaction with NLS PB1 cargo protein from Influenza A virus at 10 uM for 30 mins by pull-down assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Binding affinity to human IPO5 in human PC-3 cell lysate incubated for 30 mins by DTB-Cy3 dye based pull down analysis
Assay data:1 Active, 3 Tested
Competitive binding affinity to human IPO5 in human PC-3 cell lysate at 10 uM for 30 mins followed by GOYA-P treatment for 30 mins by DTB-Cy3 dye based pull-down assay
Competitive binding affinity to human IPO5 in human PC-3 cell lysate at 10 uM for 30 mins followed by GOYA-P treatment for 30 mins by DTB-Cy3 dye based SDS-PAGE analysis
Assay data:2 Active, 2 Tested
Binding affinity to IPO5 in human NCI-H358 cells at 1 uM by mass spectrometry based pull down assay
Binding affinity to IPO5 in human NCI-H23 cells at 1 uM by mass spectrometry based pull down assay
Target deconvolution using SILAC Measured in Biochemical System- 2143-27_Activator_Dose_CherryPick_Activity
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Inhibition of mitochondrial ETC complex 1 in human T47D cells assessed as inhibition of 1% O2-induced HIF1 activation incubated for 30 mins prior to 1% O2-challenge measured after 16 hrs by luciferase reporter assay
Assay data:4 Active, 2 Activity ≤ 1 µM, 13 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of mitochondrial ETC complex 1 in human T47D cells assessed as inhibition of 1,10-phenanthroline-induced HIF1 activation incubated for 30 mins prior to 1,10-phenanthroline-challenge measured after 16 hrs by luciferase reporter assay
Assay data:4 Active, 13 Tested
Inhibition of mitochondrial ETC complex 1 in human T47D cells assessed as inhibition of 1,10-phenanthroline-induced HIF1 activation at 30 uM incubated for 30 mins prior to 1,10-phenanthroline-challenge measured after 16 hrs by luciferase reporter assay
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of mitochondrial ETC complex 1 in human T47D cells assessed as inhibition of 1% O2-induced HIF1 activation at 30 uM incubated for 30 mins prior to 1% O2-challenge measured after 16 hrs by luciferase reporter assay
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