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Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assay
Assay data:28 Active, 21 Activity ≤ 1 µM, 30 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Activation of eIF2alpha in human CRL-2813 cells assessed as decrease in cyclin D1 expression at 5 uM measured after 8 hrs Western blot analysis
Assay data:6 Active, 7 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Activation of eIF2alpha in human CRL-2813 cells assessed as increase in CHOP expression at 5 uM measured after 8 hrs Western blot analysis
Activation of eIF2alpha in human CRL-2813 cells assessed as eIF2alpha phosphorylation at 5 uM measured after 2 hrs Western blot analysis
Activation of eIF2alpha (unknown origin) assessed as fold stimulation ATF-4 surrogate eIF2alpha phosphorylation at 5 uM cell based Dual luciferase reporter assay
Assay data:24 Tested
SummaryPubMed CitationRelated BioAssays by Target
Activation of eIF2alpha (unknown origin) assessed as fold stimulation ATF-4 surrogate eIF2alpha phosphorylation at 1.25 uM cell based Dual luciferase reporter assay
Induction of EIF2alpha phosphorylation in human A172 cells at 1 uM measured after 2 hrs by Western blot analysis
Assay data:1 Tested
Induction of EIF2alpha phosphorylation in human A172 cells at 10 ug/ml measured after 2 hrs by Western blot analysis
Assay data:1 Active, 1 Tested
Induction of EIF2alpha phosphorylation in human A172 cells at 20 uM measured after 2 hrs by Western blot analysis
Assay data:6 Active, 6 Tested
Induction of EIF2alpha phosphorylation in human U87MG cells at 1 uM measured after 2 hrs by Western blot analysis
Induction of EIF2alpha phosphorylation in human U87MG cells at 10 ug/ml measured after 2 hrs by Western blot analysis
Induction of EIF2alpha phosphorylation in human U87MG cells at 20 uM measured after 2 hrs by Western blot analysis
Inhibition of H2O2-induced eIF2alpha phosphorylation in human SH-SY5Y cells at 0.1 uM
Assay data:9 Tested
Inhibition of H2O2-induced eIF2alpha phosphorylation in human SH-SY5Y cells at 1 uM
Assay data:5 Tested
Induction of eIF2-alpha phosphorylation in human A549 cells by immunoblot analysis
Induction of eIF2alpha phosphorylation in human MCF7 cells at 3 times IC50 after 36 hrs by Western blot analysis
Assay data:3 Active, 3 Tested
Induction of phosphorylation of eIF2alpha in mouse BMDM cells at 50 uM after 90 mins by Western blot analysis
Assay data:3 Active, 5 Tested
Inhibition of eIF2alpha autophosphorylation in human A2780 cells
Assay data:2 Tested
Inhibition of eIF2alpha autophosphorylation in human MCF7 cells
Determination of inhibition of thapsigargin-initiated eIF2 alpha phosphorylation in ER stress signaling.
Assay data:11 Tested
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
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