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Binding affinity to CD81 (unknown origin) assessed as disruption of interaction between CD81 the HCV envelope protein E2 by measuring Kd for CD81/E2 interaction at 5 uM by surface plasmon resonance assay (Rvb = 1.3 nM)
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Binding affinity to CD81 (unknown origin) assessed as disruption of interaction between CD81 the HCV envelope protein E2 at 5 uM by surface plasmon resonance assay relative to untreated control
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Binding affinity to CD81 (unknown origin) assessed as dissociation rate constant by surface plasmon resonance assay
Assay data:2 Tested
Binding affinity to CD81 (unknown origin) assessed as association rate constant by surface plasmon resonance assay
Binding affinity to CD81 (unknown origin) by surface plasmon resonance assay
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Binding affinity to CD81 (unknown origin)
Inhibition of human recombinant GST-tagged CD81 protein assessed as HCV E1E2 binding after 1 hr by Western blot analysis
Assay data:6 Tested
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