Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Selectivity interaction (CEREP ligand profiling ) EUB0000351a LTB4R
Assay data:1 Active, 1 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
cAMP Assay from US Patent US10370368: "Aryl acylsulfonamides as BLT1 antagonists"
Assay data:9 Active, 9 Activity ≤ 1 µM, 9 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
BLT-1 cAMP Assay from US Patent US10336733: "Aryl acylsulfonamides as BLT1 antagonists"
Assay data:46 Active, 40 Activity ≤ 1 µM, 46 Tested
PRESTO-Tango GPCRome screening (LTB4R2B)
Assay data:1 Tested
SummaryRelated BioAssays by Target
PRESTO-Tango GPCRome screening (LTB4R)
LTB4 (h) (BLT1) CEREP ligand profiling
Binding assay (LTB4R )
BLT1/H Cerep selectivity data (BI)
Agonist activity at human BLT1 overexpressed in CHO-K1 cells assessed as accumulation of inositol monophosphate measured after 90 mins by HTRF assay
Assay data:13 Tested
SummaryPubMed CitationRelated BioAssays by Target
Agonist activity at human BLT2 overexpressed in CHO-K1 cells assessed as accumulation of inositol monophosphate by measuring efficacy at 20 uM measured after 90 mins by HTRF assay relative to CAY10583
Assay data:11 Tested
Agonist activity at human BLT2 overexpressed in CHO-K1 cells assessed as accumulation of inositol monophosphate measured after 90 mins by HTRF assay
Assay data:9 Active, 4 Activity ≤ 1 µM, 22 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of LTB4 (unknown origin) at 0.1 to 1 uM
Agonist activity at human BLT1 isoform 1 expressed in CHO-K1 cells over-expressing GNA15/16 assessed as stimulation of IP-1 accumulation at >=20 uM incubated for 90 mins by IP-one assay relative to control
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of human BLT2 isoform 2 expressed in CHO-K1 cells over-expressing GNA14 assessed as IP-1 accumulation at >50 uM incubated for 90 mins by IP-one assay relative to basal level
Agonist activity at human BLT1 isoform 1 expressed in CHO-K1 cells over-expressing GNA15/16 assessed as stimulation of IP-1 accumulation at >=10 uM incubated for 90 mins by IP-one assay relative to control
Assay data:3 Active, 3 Tested
Agonist activity at human BLT1 isoform 1 expressed in CHO-K1 cells over-expressing GNA15/16 assessed as stimulation of IP-1 accumulation incubated for 90 mins by IP-one assay relative to control
Assay data:47 Tested
Inhibition of human BLT2 isoform 2 expressed in CHO-K1 cells over-expressing GNA14 assessed as IP-1 accumulation at >10 uM incubated for 90 mins by IP-one assay relative to basal level
Assay data:2 Active, 2 Tested
Agonist activity at human BLT2 isoform 2 expressed in CHO-K1 cells over-expressing GNA14 assessed as stimulation of IP-1 accumulation incubated for 90 mins by IP-one assay relative to CAY10583
Assay data:40 Tested
Agonist activity at human BLT2 isoform 2 expressed in CHO-K1 cells over-expressing GNA14 assessed as stimulation of IP-1 accumulation incubated for 90 mins by IP-one assay
Assay data:40 Active, 32 Activity ≤ 1 µM, 51 Tested
Inhibition of human BLT2 isoform 2 expressed in CHO-K1 cells over-expressing GNA14 assessed as IP-1 accumulation at 50 uM incubated for 90 mins by IP-one assay relative to basal level
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on