Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19537661.

Antagonist activity at human pA2

Source:: ChEMBL

Protein Target:: Phospholipase A2, membrane associated

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1953766

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19537552.

Antagonist activity at rat PA2 transfected in xenopus oocyte cell

Source:: ChEMBL

Protein Target:: Phospholipase A2, membrane associated

Assay data:1 Active, 1 Tested

AID:: 1953755

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 19537393.

Antagonist activity at human pA2 by FLIPR assay

Source:: ChEMBL

Protein Target:: Phospholipase A2, membrane associated

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1953739

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19537254.

Antagonist activity at pA2 (unknown origin)

Source:: ChEMBL

Protein Target:: Phospholipase A2, membrane associated

Assay data:1 Active, 1 Tested

AID:: 1953725

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 19400895.

Inhibition of recombinant human sPLA2-V

Source:: ChEMBL

Protein Target:: Phospholipase A2, membrane associated

Assay data:7 Active, 2 Activity ≤ 1 µM, 7 Tested

AID:: 1940089

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19315156.

Inhibition of human recombinant sPLA2-V at 1 uM

Source:: ChEMBL

Protein Target:: Phospholipase A2, membrane associated

Assay data:1 Active, 1 Tested

AID:: 1931515

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 19314977.

Inhibition of recombinant human sPLA2-V

Source:: ChEMBL

Protein Target:: Phospholipase A2, membrane associated

Assay data:1 Active, 1 Tested

AID:: 1931497

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 19041128.

Inhibition of PLA2 (unknown origin)

Source:: ChEMBL

Protein Target:: Phospholipase A2

Assay data:9 Active, 2 Activity ≤ 1 µM, 14 Tested

AID:: 1904112

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 18947299.

Inhibition of human group X phospholipase A2 incubated for 10 to 20 mins cells by radiometric assay

Source:: ChEMBL

Protein Target:: Group 10 secretory phospholipase A2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1894729

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 189472810.

Inhibition of mouse group X phospholipase A2 incubated for 10 to 20 mins cells by radiometric assay

Source:: ChEMBL

Protein Target:: Group 10 secretory phospholipase A2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1894728

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 189472711.

Inhibition of mouse group IB phospholipase A2 incubated for 10 to 20 mins cells by radiometric assay

Source:: ChEMBL

Protein Target:: Phospholipase A2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1894727

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 189472612.

Inhibition of mouse group V phospholipase A2 incubated for 10 to 20 mins cells by radiometric assay

Source:: ChEMBL

Protein Target:: Phospholipase A2 group V

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1894726

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 189472513.

Inhibition of mouse group IIE phospholipase A2 incubated for 10 to 20 mins cells by radiometric assay

Source:: ChEMBL

Protein Target:: Group IIE secretory phospholipase A2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1894725

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 189472314.

Inhibition of human group IIA phospholipase A2 incubated for 10 to 20 mins cells by radiometric assay

Source:: ChEMBL

Protein Target:: Phospholipase A2, membrane associated

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1894723

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 189472215.

Inhibition of mouse group IIA phospholipase A2 incubated for 10 to 20 mins cells by radiometric assay

Source:: ChEMBL

Protein Target:: Phospholipase A2, membrane associated

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1894722

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 189472116.

Inhibition of human group IB phospholipase A2 expressed in Escherichia coli BL21 cells incubated for 10 to 20 mins cells by radiometric assay

Source:: ChEMBL

Protein Target:: Phospholipase A2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1894721

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 189472017.

Inhibition of human group V phospholipase A2 expressed in Escherichia coli BL21(DE3) cells incubated for 10 to 20 mins cells by radiometric assay

Source:: ChEMBL

Protein Target:: Phospholipase A2 group V

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1894720

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 189471918.

Inhibition of human group IIE phospholipase A2 expressed in Escherichia coli BL21 cells incubated for 10 to 20 mins cells by radiometric assay

Source:: ChEMBL

Protein Target:: Group IIE secretory phospholipase A2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1894719

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 189471819.

Inhibition of human group IIA phospholipase A2 preincubated with compound for 10 mins followed by enzyme addition and measured after 30 mins by PC/DOC assay

Source:: ChEMBL

Protein Target:: Phospholipase A2, membrane associated

Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested

AID:: 1894718

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 189471720.

Inhibition of human group IIA phospholipase A2 incubated for 30 mins by automatic plate reader analysis

Source:: ChEMBL

Protein Target:: Phospholipase A2, membrane associated

Assay data:5 Active, 4 Activity ≤ 1 µM, 7 Tested

AID:: 1894717

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

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Target

Proteins (18)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (189)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (10)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (132)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (204)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (2)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose

Assay Project (7)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (342)
BioAssays extracted from the literature
NIH MLP (8)
BioAssays deposited by the NIH Molecular Libraries Program

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