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Inhibition of HIV-1 integrase DTG-resistant H51Y/R263K double mutant
Assay data:1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of HIV-1 integrase DTG-resistant R263K mutant
Inhibition of HIV-1 integrase DTG-resistant G118R mutant
Inhibition of HIV-1 integrase Q148K mutant
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of HIV-1 integrase strand transfer activity
Assay data:10 Active, 9 Activity ≤ 1 µM, 10 Tested
Jurkat Latency Reversal Assay from US Patent US11492361: "Compounds useful in HIV therapy"
Assay data:59 Active, 59 Activity ≤ 1 µM, 59 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Inhibition of Influenza A virus (A/Wisconsin/09/2013(HIN1)) recombinant Neuraminidase using MUNANA as substrate incubated for 60 mins by fluorescence based assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
Inhibition of HIV-1 integrase strand transfer activity by enzymatic assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of recombinant HIV-1 integrase strand transfer activity by enzymatic assay
Inhibition of full-length recombinant HIV1 integrase at 1 uM using target substrate DNA preincubated for 5 mins followed by substrate addition and measured after 30 mins by colorimetry relative to control
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of full-length recombinant HIV1 integrase at 100 nM using target substrate DNA preincubated for 5 mins followed by substrate addition and measured after 30 mins by colorimetry relative to control
Inhibition of Influenza A virus H1N1 Neuraminidase
Inhibition of Influenza A virus A/California/04/2009 (H1N1) Neuraminidase H274Y mutant using MUNANA as substrate preincubated for 10 mins followed by substrate addition and measured after 40 mins by fluorescence based microplate reader method
Assay data:14 Active, 3 Activity ≤ 1 µM, 15 Tested
Binding affinity to influenza A/Beijing/262/95 H1N1 neuraminidase expressed in baculovirus expression system using sialyl-lactose as substrate
Assay data:3 Active, 2 Activity ≤ 1 µM, 3 Tested
Inhibition of Influenza A virus (A/Guangdong/05/2009(H1N1)) neuraminidase using 4-MUNANA as substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr by fluorescence assay
Inhibition of Influenza A virus (A/Guangdong/03/2009(H1N1)) neuraminidase using 4-MUNANA as substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr by fluorescence assay
Inhibition of Influenza A virus (A/GuangdongSB/01/2009(H1N1)) neuraminidase using 4-MUNANA as substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr by fluorescence assay
Inhibition of HIV-1 integrase mutant strand transfer activity incubated for 10 mins by enzymatic assay
Inhibition of HIV-1 integrase strand transfer activity incubated for 10 mins by enzymatic assay
Inhibition of recombinant HIV-1 subtype C integrase using double-stranded FITC-labelled target DNA as substrate pre-incubated for 45 mins followed by substrate addition measured after 60 mins by strand transfer inhibition assay
Assay data:1 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
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