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Inhibition of Vif-mediated human A3G degradation in HEK-293T cells cotransfected with hA3G and Vif at 20 uM by western blot analysis relative to control
Assay data:22 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of recombinant APOBEC3G C321A mutant (unknown origin) expressed in HEK293 cells assessed as reduction in cytosine deaminase activity using 5'-6-FAM and 3'-TAMRA quench molecule tagged cytosine-containing single-stranded DNA substrate incubated for 2 hrs by fluorescence-based assay
Assay data:8 Tested
SummaryRelated BioAssays by Target
Inhibition of recombinant APOBEC3A (unknown origin) expressed in HEK293 cells assessed as reduction in cytosine deaminase activity at 200 uM using 5'-6-FAM and 3'-TAMRA quench molecule tagged cytosine-containing single-stranded DNA substrate incubated for 2 hrs by fluorescence-based assay relative to control
Assay data:1 Tested
Inhibition of recombinant APOBEC3G (unknown origin) expressed in HEK293 cells assessed as cytosine deaminase efficiency at 200 uM using 5'-6-FAM and 3'-TAMRA quench molecule tagged cytosine-containing single-stranded DNA substrate incubated for 2 hrs and measured on at days 74 by fluorescence-based assay (Rvb = 100%)
Inhibition of recombinant APOBEC3G (unknown origin) expressed in HEK293 cells assessed as cytosine deaminase efficiency at 200 uM using 5'-6-FAM and 3'-TAMRA quench molecule tagged cytosine-containing single-stranded DNA substrate incubated for 2 hrs and measured on at days 38 by fluorescence-based assay (Rvb = 100%)
Inhibition of recombinant APOBEC3G (unknown origin) expressed in HEK293 cells assessed as cytosine deaminase efficiency at 200 uM using 5'-6-FAM and 3'-TAMRA quench molecule tagged cytosine-containing single-stranded DNA substrate incubated for 2 hrs and measured on at days 21 by fluorescence-based assay (Rvb = 100%)
Inhibition of recombinant APOBEC3G (unknown origin) expressed in HEK293 cells assessed as cytosine deaminase efficiency at 200 uM using 5'-6-FAM and 3'-TAMRA quench molecule tagged cytosine-containing single-stranded DNA substrate incubated for 2 hrs and measured on at days 3 by fluorescence-based assay (Rvb = 100%)
Inhibition of recombinant APOBEC3G (unknown origin) expressed in HEK293 cells assessed as reduction in cytosine deaminase activity using 5'-6-FAM and 3'-TAMRA quench molecule tagged cytosine-containing single-stranded DNA substrate incubated for 2 hrs and measured on at days 3, 21, 38, and 72 by fluorescence-based assay
Inhibition of recombinant APOBEC3G (unknown origin) expressed in HEK293 cells assessed as reduction in cytosine deaminase activity at 200 uM using 5'-6-FAM and 3'-TAMRA quench molecule tagged cytosine-containing single-stranded DNA substrate incubated for 2 hrs and measured on day 0 by fluorescence-based assay
Inhibition of recombinant APOBEC3A (unknown origin) expressed in HEK293 cells assessed as reduction in cytosine deaminase activity at 200 uM using 5'-6-FAM and 3'-TAMRA quench molecule tagged cytosine-containing single-stranded DNA substrate incubated for 2 hrs and measured on day 0 by fluorescence-based assay
Inhibition of recombinant APOBEC3G (unknown origin) expressed in HEK293 cells assessed as reduction in cytosine deaminase activity using 5'-6-FAM and 3'-TAMRA quench molecule tagged cytosine-containing single-stranded DNA substrate incubated for 2 hrs by fluorescence-based assay
Assay data:10 Tested
Inhibition of recombinant APOBEC3A (unknown origin) expressed in HEK293 cells assessed as reduction in cytosine deaminase activity using 5'-6-FAM and 3'-TAMRA quench molecule tagged cytosine-containing single-stranded DNA substrate incubated for 2 hrs by fluorescence-based assay
Assay data:1 Active, 11 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Binding affinity to FLAG-tagged human A3G expressed in human 293T cells at 13 uM incubated for 16 hrs in presence of EDTA by streptavidin agarose based immunoblot analysis
Binding affinity to FLAG-tagged human A3G expressed in human 293T cells at 13 uM incubated for 16 hrs by streptavidin agarose based immunoblot analysis
Assay data:1 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of APOBEC3G (unknown origin) using ssDNA oligomer 5'-6-FAM-AAA-TAT-TCC-CTA-ATA-GAT-AAT-GTG-A-TAMRA-3' by fluorescence-based deamination HTS assay
Inhibition of APOBEC3G (unknown origin) using ssDNA oligomer 5'-6-FAM-AAA-TAT-TCC-CTA-ATA-GAT-AAT-GTG-A-TAMRA-3' by fluorescence-based deamination assay
Inhibition of APOBEC3G (unknown origin) assessed as reduction enzyme efficiency at 200 uM using ssDNA oligomer 5'-6-FAM-AAA-TAT-TCC-CTA-ATA-GAT-AAT-GTG-A-TAMRA-3' by fluorescence-based deamination assay
Inhibition of APOBEC3G (unknown origin) assessed as remaining enzyme activity at 200 uM using ssDNA oligomer 5'-6-FAM-AAA-TAT-TCC-CTA-ATA-GAT-AAT-GTG-A-TAMRA-3' by fluorescence-based deamination assay
Assay data:5 Tested
Inhibition of APOBEC3G (unknown origin) assessed as remaining enzyme activity at 200 uM incubated for 74 days using ssDNA oligomer 5'-6-FAM-AAA-TAT-TCC-CTA-ATA-GAT-AAT-GTG-A-TAMRA-3' by fluorescence-based deamination assay
Inhibition of APOBEC3G (unknown origin) assessed as remaining enzyme activity at 200 uM incubated for 38 days using ssDNA oligomer 5'-6-FAM-AAA-TAT-TCC-CTA-ATA-GAT-AAT-GTG-A-TAMRA-3' by fluorescence-based deamination assay
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