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Inhibition of survivin dimerization in human PC-3 cells assessed as survivin degradation at 500 nM incubated for 24 hrs after 2 hrs pretreatment with proteasome inhibitor MG132 by Western blot analysis
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of survivin dimerization in human PC-3 cells assessed as survivin degradation at 500 nM incubated for 24 hrs after 2 hrs pretreatment with proteasome inhibitor bortezomib by Western blot analysis
Inhibition of survivin dimerization in human LNCaP C4-2 cells assessed as survivin degradation at 500 nM incubated for 24 hrs after 2 hrs pretreatment with proteasome inhibitor MG132 by Western blot analysis
Inhibition of survivin dimerization in human LNCaP C4-2 cells assessed as survivin degradation at 500 nM incubated for 24 hrs after 2 hrs pretreatment with proteasome inhibitor bortezomib by Western blot analysis
Inhibition of survivin dimerization in human PC-3 cells assessed as survivin degradation at 500 nM incubated for 24 hrs by Western blot analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of survivin dimerization in human LNCaP C4-2 cells assessed as survivin degradation at 500 nM incubated for 24 hrs by Western blot analysis
Inhibition of survivin dimerization in human PC-3 cells assessed as survivin degradation at 1 uM incubated for 24 hrs by Western blot analysis
Assay data:2 Active, 2 Tested
Inhibition of survivin dimerization in human LNCaP C4-2 cells assessed as survivin degradation at 1 uM incubated for 24 hrs by Western blot analysis
Inhibition of survivin-GAL4-DBD dimerization (unknown origin) expressed in human LNCaP C4-2 cells incubated for 24 hrs by SEAP reporter based mammalian two hybrid assay
Binding affinity to human survivin expressed in Escherichia coli BL21 assessed as dissociation constant measured by Surface plasmon resonance
Suppression of survivin in human MDA-MB-453 cells after 72 hrs by immunoblot analysis
Suppression of survivin in human BT-20 cells after 72 hrs by immunoblot analysis
Suppression of survivin in human MDA-MB-231 cells after 72 hrs by immunoblot analysis
Inhibition of survivin in human MDA-MB-453 cells assessed as reduction in survivin mRNA expression measured after 72 hrs by qPCR analysis
Assay data:3 Active, 3 Tested
Inhibition of survivin in human BT-20 cells assessed as reduction in survivin mRNA expression measured after 72 hrs by qPCR analysis
Inhibition of survivin in human MDA-MB-231 cells assessed as reduction in survivin mRNA expression measured after 72 hrs by qPCR analysis
Binding affinity to survivin monomer in human HeLa cells assessed as fluorescence signal in centromere at 10 uM by immunofluorescence based confocal laser scanning microscopy
Binding affinity to survivin dimer in human HeLa cells assessed as fluorescence signal in centromere at 10 uM by immunofluorescence based confocal laser scanning microscopy
Binding affinity to survivin in human HeLa cells assessed as fluorescence signal at 10 uM by immunofluorescence based confocal laser scanning microscopy
Binding affinity to survivin in G2/M phase synchronized human HeLa cells assessed as fluorescence signal in cytoplasm at 10 uM by immunofluorescence based confocal laser scanning microscopy
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