Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19618341.

Antagonist activity at human RARG in an in vitro cell-based assay measured by time-resolved fluorescence resonance energy transfer method

Source:: ChEMBL

Protein Target:: Retinoic acid receptor gamma

Assay data:5 Active, 36 Tested

AID:: 1961834

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 19618332.

Agonist activity at human RARG in an in vitro cell-based assay measured by time-resolved fluorescence resonance energy transfer method

Source:: ChEMBL

Protein Target:: Retinoic acid receptor gamma

Assay data:1 Active, 38 Tested

AID:: 1961833

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 19618303.

Antagonist activity at human RARA in an in vitro cell-based assay measured by time-resolved fluorescence resonance energy transfer method

Source:: ChEMBL

Protein Target:: Retinoic acid receptor alpha

Assay data:36 Tested

AID:: 1961830

Summary PubMed Citation Related BioAssays by Target

Select item 19618294.

Agonist activity at human RARA in an in vitro cell-based assay measured by time-resolved fluorescence resonance energy transfer method

Source:: ChEMBL

Protein Target:: Retinoic acid receptor alpha

Assay data:1 Active, 38 Tested

AID:: 1961829

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 19616645.

Agonist activity at human RAR-alpha assessed as receptor transactivation at 500 to 20000 nM incubated for 24 hrs by luciferase reporter gene assay

Source:: ChEMBL

Protein Target:: Retinoic acid receptor alpha

Assay data:1 Tested

AID:: 1961664

Summary PubMed Citation Related BioAssays by Target

Select item 19616626.

Agonist activity at human RAR-alpha assessed as receptor transactivation incubated for 24 hrs by luciferase reporter gene assay

Source:: ChEMBL

Protein Target:: Retinoic acid receptor alpha

Assay data:1 Tested

AID:: 1961662

Summary PubMed Citation Related BioAssays by Target

Select item 19601067.

Agonist activity at human RORgammat

Source:: ChEMBL

Protein Target:: Nuclear receptor ROR-gamma

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1960106

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19601058.

Inverse agonist activity at human RORgammat

Source:: ChEMBL

Protein Target:: Nuclear receptor ROR-gamma

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1960105

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19600969.

Inhibition of human RORgammmat LBD expressed in HEK293T by two-hybrid reporter assay

Source:: ChEMBL

Protein Target:: Nuclear receptor ROR-gamma

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1960096

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 196009510.

Inhibition of human RORgammmat LBD expressed in HEK293T by one-hybrid reporter assay

Source:: ChEMBL

Protein Target:: Nuclear receptor ROR-gamma

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1960095

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 196009411.

Inhibition of human RORgammmat LBD expressed in Escherichia coli by FRET co-activator peptide assay

Source:: ChEMBL

Protein Target:: Nuclear receptor ROR-gamma

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1960094

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 196009312.

Inhibition of human RORgammmat LBD expressed in Escherichia coli by ThermoFluro assay

Source:: ChEMBL

Protein Target:: Nuclear receptor ROR-gamma

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1960093

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 196009213.

Inhibition of GAL4-RORgammat LBD (unknown origin)

Source:: ChEMBL

Protein Target:: Nuclear receptor ROR-gamma

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1960092

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 196009114.

Inhibition of RORgammat LBD (unknown origin) expressed in Sf21 cells assessed as fluorescence signal by TR-FRET assay

Source:: ChEMBL

Protein Target:: Nuclear receptor ROR-gamma

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1960091

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 196009015.

Inverse agonist activity at human GAL4-RORgamma DBD expressed in HEK293 cells measured after 24 hrs by ligand binding assay

Source:: ChEMBL

Protein Target:: Nuclear receptor ROR-gamma

Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 1960090

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 196008916.

Inverse agonist activity at GAL4-RORgammat LBD (unknown origin) expressed in HEK293 cells at 1 uM measured after 24 hrs by nuclear receptor assay relative to control

Source:: ChEMBL

Protein Target:: Nuclear receptor ROR-gamma

Assay data:1 Tested

AID:: 1960089

Summary PubMed Citation Related BioAssays by Target

Select item 196008417.

Inverse agonist activity at GAL4-RORgammat LBD (unknown origin) expressed in HEK293 cells measured after 18 to 24 hrs by nuclear receptor assay

Source:: ChEMBL

Protein Target:: Nuclear receptor ROR-gamma

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1960084

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 196008318.

Inhibition of biotinylated human RORgammat by FRET assay

Source:: ChEMBL

Protein Target:: Nuclear receptor ROR-gamma

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1960083

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 196008019.

Inhibition of human GAL4-fused RORgammat LBD transfected in Escherichia coli BL21(DE3) cell measured after 16 hrs by HTRF assay

Source:: ChEMBL

Protein Target:: Nuclear receptor ROR-gamma

Assay data:5 Active, 5 Activity ≤ 1 µM, 5 Tested

AID:: 1960080

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 196007220.

Inhibition of RORgammat (unknown origin) by cell based reporter gene assay

Source:: ChEMBL

Protein Target:: Nuclear receptor ROR-gamma

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1960072

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

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Target

Proteins (34)
BioAssays with protein sequences specified as targets

BioActivity

Chemical Probes (2)
BioAssays with compounds reported as validated chemical probes

Active Compounds (884)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (114)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (729)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (6)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (913)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (5)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose

Assay Project (34)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (1,427)
BioAssays extracted from the literature
NIH MLP (30)
BioAssays deposited by the NIH Molecular Libraries Program
Other (11)
BioAssays deposited by other experimentalists

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