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Cross screening panel
Assay data:1 Tested
SummaryRelated BioAssays by Target
Safety47 Scan (DiscoverX - Eurofins)
Histamine H1 Eurofins Panlabs panel
H1/PYRIL/HS Eurofins SafetyScreen44 (BI)
Binding affinity towards human HRH1 in an in vitro assay measured by filtration
Assay data:151 Active, 1 Activity ≤ 1 nM, 90 Activity ≤ 1 µM, 1239 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Antagonist activity at human HRH1 in an in vitro cell-based assay measured by fluorescent imaging plate reader
Assay data:23 Active, 13 Activity ≤ 1 µM, 168 Tested
Agonist activity at human HRH1 in an in vitro cell-based assay measured by fluorescent imaging plate reader
Assay data:1 Active, 170 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of histamine H1 receptor (unknown origin) upto 10000 nM
SummaryPubMed CitationRelated BioAssays by Target
Displacement of [3H]pyrilamine from recombinant human histamine H1 receptor expressed in CHO-K1 cell membrane at 1 uM incubated for 30 mins by liquid scintillation counter analysis relative to control
Displacement of [3H]pyrilamine from human recombinant histamine H1 receptor at 10 uM after 60 mins by scintillation counting analysis relative to control
Assay data:3 Tested
Antagonist potency at human histamine H1 receptor
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
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