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VEGFR ADP GLO Assay from US Patent US20240109917: "PYRAZOLOTHIAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS"
Assay data:23 Active, 13 Activity ≤ 1 µM, 485 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Electrophoretic Mobility Shift Assay (MSA) from US Patent US20240109877: "PYRIMIDINES FOR DEGRADING BRUTON'S TYROSINE KINASE"
Assay data:19 Active, 19 Activity ≤ 1 nM, 19 Activity ≤ 1 µM, 19 Tested
Kinase Assay from US Patent US20240109865: "INDAZOLE COMPOUNDS AS KINASE INHIBITORS"
Assay data:359 Active, 363 Activity ≤ 1 µM, 363 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
JAK2 Z-Lyte Biochemical Assay from US Patent US20240101559: "TRICYCLIC KINASE INHIBITORS AND USES THEREOF"
Assay data:9 Active, 1 Activity ≤ 1 µM, 11 Tested
ADP-Glo Kinase Assay from US Patent US20240101538: "PROTEIN-PROTEIN INTERACTION MODULATORS OF AURORA KINASE A AND THEIR USE IN THE PREVENTION AND/OR TREATMENT OF CANCER"
Assay data:3 Active, 3 Activity ≤ 1 µM, 10 Tested
ABL1 Biochemical Kinase Assay from US Patent US20240101536: "COMPOUNDS FOR TREATING CERTAIN LEUKEMIAS"
Assay data:217 Active, 190 Activity ≤ 1 nM, 217 Activity ≤ 1 µM, 217 Tested
Biochemical JAK Kinase Assays from US Patent US20240092758: "IMIDAZOLO INDAZOLE COMPOUNDS AS JAK INHIBITORS"
Assay data:392 Active, 381 Activity ≤ 1 nM, 392 Activity ≤ 1 µM, 392 Tested
Adenosine Receptor Time-Resolved Fluorescence Resonance Energy Transfer (TRFRET) Binding Assay from US Patent US20240083904: "ANTAGONISTS OF THE ADENOSINE A2A RECEPTOR"
Assay data:13 Active, 10 Activity ≤ 1 nM, 13 Activity ≤ 1 µM, 13 Tested
In Vitro BTK Kinase Assay: Btk-PolyGAT-LS Assay from US Patent US20240083900: "PYRAZOLO[1,5-A]PYRAZINE DERIVATIVES AS BTK INHIBITORS"
Assay data:228 Active, 80 Activity ≤ 1 nM, 228 Activity ≤ 1 µM, 228 Tested
5-HT2A Receptor Binding Inhibition Assay from US Patent US20240083872: "CYCLIC AMINE DERIVATIVES HAVING SEROTONIN RECEPTOR BINDING ACTIVITY"
Assay data:126 Active, 12 Activity ≤ 1 nM, 118 Activity ≤ 1 µM, 126 Tested
Determination of Binding Constants to Menin-MLL from US Patent US11919901: "Inhibitors of the menin-MLL interaction"
Assay data:253 Active, 249 Activity ≤ 1 nM, 253 Activity ≤ 1 µM, 253 Tested
In Vitro Test of Activities of Jak1, Jak2, Jak3, Tyk2 Kinases from US Patent US11919896: "[1,2,4]triazolo[1,5-a]pyridine compound as JAK inhibitor and use thereof"
Assay data:34 Active, 22 Activity ≤ 1 µM, 34 Tested
AlphaScreen Assay from US Patent US11919855: "Substituted pyrrolidones and piperidones as small molecule inhibitors of EZH2 and EED protein binding"
Assay data:30 Active, 9 Activity ≤ 1 µM, 103 Tested
Binding Assay from US Patent US20240067637: "NAPHTHYRIDINE AND PYRIDO[3,4-c]PYRIDAZINE DERIVATIVES AS GABAA ALPHA 5 RECEPTOR MODULATORS"
Assay data:44 Active, 1 Activity ≤ 1 nM, 44 Activity ≤ 1 µM, 44 Tested
Patch Clamp Electrophysiology from US Patent US11912737: "19-nor neuroactive steroids and methods of use thereof"
Assay data:2 Active, 3 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Target
Steroid Inhibition of TBPS Binding from US Patent US11912737: "19-nor neuroactive steroids and methods of use thereof"
Assay data:4 Active, 47 Activity ≤ 1 µM, 47 Tested
Mobility-Shift Assay from US Patent US11912663: "Multi-targeted tyrosine kinase inhibitors and their pharmaceutical uses"
Assay data:14 Active, 15 Activity ≤ 1 µM, 15 Tested
TBD from US Patent US20240059694: "COMPOUND CONTAINING 1,3-BENZODIOXOL STRUCTURE AND PREPARATION METHOD AND USE THEREOF"
Assay data:30 Active, 30 Activity ≤ 1 µM, 30 Tested
In Vitro Kinase Binding Assay from US Patent US20240058459: "DENDRIMER COMPOSITIONS AND METHODS FOR DRUG DELIVERY TO THE EYE"
Assay data:3 Active, 2 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 3 Tested
Radioligand Binding Assay from US Patent US20240051978: "3-CYCLIC AMINE-INDOLE DERIVATIVES AS SEROTONERGIC AGENTS FOR THE TREATMENT OF CNS DISORDERS"
Assay data:4 Active, 3 Activity ≤ 1 µM, 4 Tested
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