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ChEMBL_158313 (CHEMBL763370) from Article 10.1016/j.bmc.2016.05.029: "Anion inhibition profiles of a-, - and -carbonic anhydrases from the pathogenic bacterium Vibrio cholerae."
Assay data:1 Active, 1 Activity ≤ 1 µM, 34 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
ChEMBL_158312 (CHEMBL763369) from Article 10.1016/j.bmc.2016.05.029: "Anion inhibition profiles of a-, - and -carbonic anhydrases from the pathogenic bacterium Vibrio cholerae."
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of Methanosarcina thermophila recombinant carbonic anhydrase gamma assessed as inhibition of CO2 hydration preincubated for 15 mins by Lineweaver-burk plot method
Assay data:1 Active, 1 Activity ≤ 1 µM, 38 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Effect on recombinant Methanosarcina thermophila carbonic anhydrase assessed as effect on Km incubated for 15 mins prior to testing by stopped flow CO2 hydration assay
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Activation of recombinant Methanosarcina thermophila gamma carbonic anhydrase assessed as Kcat at 10 uM incubated for 15 mins prior to testing by stopped flow CO2 hydration assay
Activation of recombinant Methanosarcina thermophila gamma carbonic anhydrase at 10 uM incubated for 15 mins prior to testing by stopped flow CO2 hydration assay
Assay data:19 Tested
Inhibition of Methanosarcina thermophila gamma carbonic anhydrase preincubated for 15 mins by stopped-flow CO2 hydrase assay
Inhibition of archaeon Methanosarcina thermophila gamma-CA after 15 mins by stopped-flow/Co2 hydration assay
Inhibition of Methanosarcina thermophila recombinant gamma-CA by CO2 hydration assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 36 Tested
Inhibitory activity against alpha carbonic anhydrase (Zn-Cam) from Methanosarcina thermophila
Assay data:21 Active, 18 Activity ≤ 1 µM, 22 Tested
Inhibitory activity against alpha carbonic anhydrase (Co-Cam) from Methanosarcina thermophila
Assay data:22 Active, 13 Activity ≤ 1 µM, 22 Tested
Inhibitory constant against Zn-Cam (Methanosarcina thermophila)
Assay data:22 Tested
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