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Inhibition of MuSK (unknown origin) at 1 uM relative to control
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
Selectivity interaction (ScanMAX (DiscoverX)) EUB0000005b MUSK
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Selectivity interaction (KinomeScan (DiscoverX)) EUB0000147b MUSK
Assay data:1 Tested
SummaryRelated BioAssays by Target
Selectivity interaction (Ambit kinome screening platform (Ambit phage-based competition binding assay)) EUB0000624a MUSK
Inhibition of MUSK (unknown origin) at 0.1 uM relative to control
Inhibition of MUSK (unknown origin) at 10 nM relative to control
Inhibition of MUSK (unknown origin) by Nano-syn mobility shift assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
MUSK DiscoveRx kinase panel
MuSK(h) Kinase panel
MuSK(h) Millipore kinase panel
Inhibition of MUSK (unknown origin) at 1 uM
Inhibition of human MUSK expressed in baculovirus expression system by mobility shift assay
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of human MUSK expressed in baculovirus expression system at 0.3 uM by mobility shift assay
Inhibition of human recombinant MuSK assessed as reduction in substrate phosphorylation at 500 nM using ATP and Ulight-CKKSRGDYMTMQIG (IRS-1) incubated for 60 min by LANCE detection method
Inhibition of human recombinant MuSK assessed as reduction in substrate phosphorylation at 50 nM using ATP and Ulight-CAGAGAIETDKEYYTVKD as substrate incubated for 120 min by LANCE detection method
KinomeScan assay: inhibition of MUSK
Assay data:108 Tested
MUSK(MUSKLGY1) Takeda global kinase panel
Assay data:1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, activity ≤ 1 µMRelated BioAssays by Target
MuSK(h) Eurofins kinase panel
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