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Inhibition of Nurr1-RXRalpha in HEK293T cells by BRET assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of human full length Nurr1-RXRalpha transfected in COS7 cells
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of Nurr1-RXRalpha (unknown origin) by BRET assay
Inhibition of full-length Nurr1-RXRalpha in human SH-SY5Y cells
Inhibition of full-length Nurr1 in rat N27-A cells
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of Gal4-fused Nurr1 in mouse MN9D cells
Inverse agonist activity at Gal4-fused Nurr1 (unknown origin) assessed as remaining activity relative to control
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inverse agonist activity at Gal4-fused Nurr1 (unknown origin)
Inverse agonist activity at Nurr1 (unknown origin) assessed as remaining activity relative to control
Assay data:3 Tested
Inverse agonist activity at Nurr1 (unknown origin)
Assay data:2 Active, 3 Tested
Agonist activity at human Nurr1 measured by Gal4-Nurr1 hybrid reporter gene assay
Assay data:4 Active, 1 Activity ≤ 1 µM, 4 Tested
Binding affinity towards Nurr1 ligand binding domain (unknown origin) measured by microscale thermophoresis (MST) method
Assay data:1 Active, 2 Tested
Agonist activity at Nurr1 (unknown origin)
Agonist activity at Nurr1 ligand binding domain (unknown origin) measured by Gal4-based reporter gene assay
Agonist activity at Nurr1 in rat N27-A cells measured by Gal4-based luciferase reporter gene assay
Assay data:2 Active, 2 Tested
Agonist activity at Nurr1 in rat N27-A cells measured by NBRE-based luciferase reporter gene assay
Agonist activity at Nurr1 in mouse MN9D cells measured by Gal4-based luciferase reporter gene assay
Agonist activity at Nurr1 in mouse MN9D cells measured by NBRE-based luciferase reporter gene assay
Agonist activity at Nurr1 in human SK-N-BE(2)-C cells measured by Gal4-based luciferase reporter gene assay
Agonist activity at Nurr1 in human SK-N-BE(2)-C cells measured by NBRE-based luciferase reporter gene assay
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