Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19251721.

Inhibition of Nurr1-RXRalpha in HEK293T cells by BRET assay

Source:: ChEMBL

Protein Targets:: Nuclear receptor subfamily 4 group A member 2; ...
Total:: 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1925172

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19251712.

Inhibition of human full length Nurr1-RXRalpha transfected in COS7 cells

Source:: ChEMBL

Protein Targets:: Nuclear receptor subfamily 4 group A member 2; ...
Total:: 2

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1925171

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19251683.

Inhibition of Nurr1-RXRalpha (unknown origin) by BRET assay

Source:: ChEMBL

Protein Targets:: Nuclear receptor subfamily 4 group A member 2; ...
Total:: 2

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1925168

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19251654.

Inhibition of full-length Nurr1-RXRalpha in human SH-SY5Y cells

Source:: ChEMBL

Protein Targets:: Nuclear receptor subfamily 4 group A member 2; ...
Total:: 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1925165

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19251635.

Inhibition of full-length Nurr1 in rat N27-A cells

Source:: ChEMBL

Protein Target:: Nuclear receptor subfamily 4 group A member 2

Assay data:1 Active, 1 Tested

AID:: 1925163

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 19251626.

Inhibition of Gal4-fused Nurr1 in mouse MN9D cells

Source:: ChEMBL

Protein Target:: Nuclear receptor subfamily 4 group A member 2

Assay data:1 Active, 1 Tested

AID:: 1925162

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 18852147.

Inverse agonist activity at Gal4-fused Nurr1 (unknown origin) assessed as remaining activity relative to control

Source:: ChEMBL

Protein Target:: Nuclear receptor subfamily 4 group A member 2

Assay data:2 Tested

AID:: 1885214

Summary PubMed Citation Related BioAssays by Target

Select item 18852138.

Inverse agonist activity at Gal4-fused Nurr1 (unknown origin)

Source:: ChEMBL

Protein Target:: Nuclear receptor subfamily 4 group A member 2

Assay data:2 Tested

AID:: 1885213

Summary PubMed Citation Related BioAssays by Target

Select item 18852129.

Inverse agonist activity at Nurr1 (unknown origin) assessed as remaining activity relative to control

Source:: ChEMBL

Protein Target:: Nuclear receptor subfamily 4 group A member 2

Assay data:3 Tested

AID:: 1885212

Summary PubMed Citation Related BioAssays by Target

Select item 188521110.

Inverse agonist activity at Nurr1 (unknown origin)

Source:: ChEMBL

Protein Target:: Nuclear receptor subfamily 4 group A member 2

Assay data:2 Active, 3 Tested

AID:: 1885211

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 188521011.

Agonist activity at human Nurr1 measured by Gal4-Nurr1 hybrid reporter gene assay

Source:: ChEMBL

Protein Target:: Nuclear receptor subfamily 4 group A member 2

Assay data:4 Active, 1 Activity ≤ 1 µM, 4 Tested

AID:: 1885210

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 188520912.

Binding affinity towards Nurr1 ligand binding domain (unknown origin) measured by microscale thermophoresis (MST) method

Source:: ChEMBL

Protein Target:: Nuclear receptor subfamily 4 group A member 2

Assay data:1 Active, 2 Tested

AID:: 1885209

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 188520813.

Agonist activity at Nurr1 (unknown origin)

Source:: ChEMBL

Protein Target:: Nuclear receptor subfamily 4 group A member 2

Assay data:2 Tested

AID:: 1885208

Summary PubMed Citation Related BioAssays by Target

Select item 188520714.

Agonist activity at Nurr1 ligand binding domain (unknown origin) measured by Gal4-based reporter gene assay

Source:: ChEMBL

Protein Target:: Nuclear receptor subfamily 4 group A member 2

Assay data:2 Tested

AID:: 1885207

Summary PubMed Citation Related BioAssays by Target

Select item 188520615.

Agonist activity at Nurr1 in rat N27-A cells measured by Gal4-based luciferase reporter gene assay

Source:: ChEMBL

Protein Target:: Nuclear receptor subfamily 4 group A member 2

Assay data:2 Active, 2 Tested

AID:: 1885206

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 188520516.

Agonist activity at Nurr1 in rat N27-A cells measured by NBRE-based luciferase reporter gene assay

Source:: ChEMBL

Protein Target:: Nuclear receptor subfamily 4 group A member 2

Assay data:2 Active, 2 Tested

AID:: 1885205

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 188520417.

Agonist activity at Nurr1 in mouse MN9D cells measured by Gal4-based luciferase reporter gene assay

Source:: ChEMBL

Protein Target:: Nuclear receptor subfamily 4 group A member 2

Assay data:2 Active, 2 Tested

AID:: 1885204

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 188520318.

Agonist activity at Nurr1 in mouse MN9D cells measured by NBRE-based luciferase reporter gene assay

Source:: ChEMBL

Protein Target:: Nuclear receptor subfamily 4 group A member 2

Assay data:2 Active, 2 Tested

AID:: 1885203

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 188520219.

Agonist activity at Nurr1 in human SK-N-BE(2)-C cells measured by Gal4-based luciferase reporter gene assay

Source:: ChEMBL

Protein Target:: Nuclear receptor subfamily 4 group A member 2

Assay data:2 Active, 2 Tested

AID:: 1885202

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 188520120.

Agonist activity at Nurr1 in human SK-N-BE(2)-C cells measured by NBRE-based luciferase reporter gene assay

Source:: ChEMBL

Protein Target:: Nuclear receptor subfamily 4 group A member 2

Assay data:2 Active, 2 Tested

AID:: 1885201

Summary Compounds, Active PubMed Citation Related BioAssays by Target

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Target

Proteins (2)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (116)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (4)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (10)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (34)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (1)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose

Assay Project (2)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (209)
BioAssays extracted from the literature
NIH MLP (2)
BioAssays deposited by the NIH Molecular Libraries Program

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