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Panlabs assay PDE2A
Assay data:1 Tested
SummaryRelated BioAssays by Target
3H-cAMP and 3H-cGMP Scintillation Proximity Assay (PDE2A)
Inhibition of PDE2A (unknown origin) by 3H-cAMP scintillation proximity assay
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of human PDE2A
Assay data:5 Active, 5 Activity ≤ 1 µM, 5 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of PDE2A (unknown origin)
Assay data:3 Active, 2 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 3 Tested
Inhibition of human PDE2
Assay data:4 Active, 1 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 4 Tested
Inhibition of human recombinant PDE2A using [3H]-cAMP as substrate incubated for 30 mins by radiometric based liquid scintillation analysis
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
Inhibition of human recombinant PDE2A using cGMP as substrate
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Biological Assay from US Patent US11691977: "Cyclic ether derivatives of pyrazolo[1,5-A]pyrimidine-3-carboxyamide"
Assay data:82 Active, 77 Activity ≤ 1 µM, 82 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Selectivity interaction (Eurofins CEREP Diversity Profiling (71 receptors, ion channels, and 25 other enzymes)) EUB0000231c PDE2A
Selectivity interaction (CEREP panel (LeadProfilingScreen Eurofins, panel of receptors, ion channels, and other enzymes)) EUB0000191c PDE2A
Selectivity interaction (PDE panel (enzymatic activity assay)) EUB0000751a PDE2A
Assay data:1 Active, 1 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Selectivity interaction (PDE panel (enzymatic assay)) EUB0000744a PDE2A
Inhibition of PDE2A (580 to 919 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]-cGMP as substrate measured for 15 mins by liquid scintillation counter method
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of PDE2A (580 to 919 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H-GMP] or [3H-AMP] as substrate incubated for 15 mins by liquid scintillation counting method
Inhibition of full length human PDE2A using [3H]-cGMP as substrate at <5 uM incubated for 60 mins by microbeta scintillation counter analysis
Inhibition of full length human PDE2A using [3H]-cGMP as substrate incubated for 60 mins by microbeta scintillation counter analysis
Inhibition of PDE2 (unknown origin)
Assay data:3 Active, 1 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 3 Tested
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