Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19628991.

CLK3 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Dual specificity protein kinase CLK3

Assay data:1 Tested

AID:: 1962899

Summary Related BioAssays by Target

Select item 19627952.

CLK3 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Dual specificity protein kinase CLK3

Assay data:1 Tested

AID:: 1962795

Summary Related BioAssays by Target

Select item 19626983.

CLK3 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Dual specificity protein kinase CLK3

Assay data:1 Tested

AID:: 1962698

Summary Related BioAssays by Target

Select item 19625994.

CLK3 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Dual specificity protein kinase CLK3

Assay data:1 Tested

AID:: 1962599

Summary Related BioAssays by Target

Select item 19476805.

Inhibition of recombinant human CLK3 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scintillation counter analysis

Source:: ChEMBL

Protein Target:: Dual specificity protein kinase CLK3

Assay data:31 Active, 11 Activity ≤ 1 µM, 56 Tested

AID:: 1947680

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19340016.

Inhibition of CLK3 (unknown origin)

Source:: ChEMBL

Protein Target:: Dual specificity protein kinase CLK3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1934001

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19339927.

Inhibition of human CLK3 at 12 degree celcius

Source:: ChEMBL

Protein Target:: Dual specificity protein kinase CLK3

Assay data:1 Active, 1 Tested

AID:: 1933992

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 19339888.

Inhibition of human CLK3 administered orally

Source:: ChEMBL

Protein Target:: Dual specificity protein kinase CLK3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1933988

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19339839.

Inhibition of human CLK3 assessed as residual activity at 3 uM

Source:: ChEMBL

Protein Target:: Dual specificity protein kinase CLK3

Assay data:1 Tested

AID:: 1933983

Summary PubMed Citation Related BioAssays by Target

Select item 193396810.

Inhibition of human CLK3

Source:: ChEMBL

Protein Target:: Dual specificity protein kinase CLK3

Assay data:13 Active, 16 Activity ≤ 1 µM, 22 Tested

AID:: 1933968

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 193226611.

Inhibition of CLK3 (unknown origin)

Source:: ChEMBL

Protein Target:: Dual specificity protein kinase CLK3

Assay data:1 Active, 1 Tested

AID:: 1932266

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 191370212.

Selectivity interaction (Enzymatic assay (Invitrogen)) EUB0000642a CLK3

Source:: ChEMBL

Protein Target:: Dual specificity protein kinase CLK3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913702

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191347413.

Selectivity interaction (Kinase panel (Millipore, radiometric filter-binding assay, conc. ATP = Km)) EUB0000613a CLK3

Source:: ChEMBL

Protein Target:: Dual specificity protein kinase CLK3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913474

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191315714.

Affinity Biochemical interaction (Enzymatic inhibition assay) EUB0000321b CLK3

Source:: ChEMBL

Protein Target:: Dual specificity protein kinase CLK3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913157

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191273915.

Affinity Phenotypic Cellular interaction (Changed alternative splicing pattern determined by mRNAseq) EUB0000321b CLK3

Source:: ChEMBL

Protein Target:: Dual specificity protein kinase CLK3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1912739

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191251816.

Thermal Shift Assay. Domain: start/stop: R134-T484

Source:: ChEMBL

Protein Target:: Dual specificity protein kinase CLK3

Assay data:27 Tested

AID:: 1912518

Summary Related BioAssays by Target

Select item 187188217.

Inhibition of GST-fused mouse recombinant CLK2 expressed in Escherichia coli at 10 uM using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presence of ATP by scintillation counting method

Source:: ChEMBL

Protein Target:: Dual specificity protein kinase CLK2

Assay data:6 Tested

AID:: 1871882

Summary PubMed Citation Related BioAssays by Target

Select item 187188118.

Inhibition of mouse recombinant GST-fused CLK2 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presence of ATP by scintillation counting method

Source:: ChEMBL

Protein Target:: Dual specificity protein kinase CLK2

Assay data:44 Active, 28 Activity ≤ 1 µM, 57 Tested

AID:: 1871881

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 187187819.

Inhibition of GST-fused mouse recombinant CLK3 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presence of ATP by scintillation counting method

Source:: ChEMBL

Protein Target:: Dual specificity protein kinase CLK3

Assay data:33 Active, 10 Activity ≤ 1 µM, 50 Tested

AID:: 1871878

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 187187720.

Inhibition of GST-fused mouse recombinant CLK3 expressed in Escherichia coli at 10 uM using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presence of ATP by scintillation counting method

Source:: ChEMBL

Protein Target:: Dual specificity protein kinase CLK3

Assay data:13 Tested

AID:: 1871877

Summary PubMed Citation Related BioAssays by Target

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Target

Proteins (5)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (77)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (1)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (55)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (81)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

Assay Project (3)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (170)
BioAssays extracted from the literature
NIH MLP (4)
BioAssays deposited by the NIH Molecular Libraries Program
Other (40)
BioAssays deposited by other experimentalists

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