Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19558731.

Inhibition of PI3Kalpha (unknown origin) using PIP2:PS as substrate preincubated for 1 hr followed by ATP and substate addition and measured after 1 hr by ADP-glo reagent based assay

Source:: ChEMBL

Protein Target:: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

Assay data:22 Active, 2 Activity ≤ 1 µM, 48 Tested

AID:: 1955873

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19498352.

Inhibition of PI3Kalpha (unknown origin)

Source:: ChEMBL

Protein Target:: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1949835

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19494203.

Inhibition of PI3K-p110alpha (unknown origin) incubated for 30 mins by fluorescence polarization assay

Source:: ChEMBL

Protein Target:: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1949420

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19494184.

Inhibition of recombinant PI3K p110alpha/p85 (unknown origin) incubated for 1 hr in presence of gamma[33P]ATP by scintillation counting analysis

Source:: ChEMBL

Protein Targets:: Phosphatidylinositol 3-kinase regulatory subunit alpha; ...
Total:: 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1949418

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19457905.

Inhibition of PI3Kalpha (unknown origin) preincubated for 10 mins followed by ATP addition and measured after 60 mins by ADP-Glo assay

Source:: ChEMBL

Protein Target:: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

Assay data:1 Active, 1 Tested

AID:: 1945790

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 19421366.

Inhibition of PI3Kalpha (unknown origin)

Source:: ChEMBL

Protein Target:: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1942136

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19406197.

Inhibition of PI3Kalpha (unknown origin)

Source:: ChEMBL

Protein Target:: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested

AID:: 1940619

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19400268.

Binding affinity to PI3Kalpha (unknown origin) assessed as dissociation constant

Source:: ChEMBL

Protein Target:: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

Assay data:1 Tested

AID:: 1940026

Summary PubMed Citation Related BioAssays by Target

Select item 19373679.

Inhibition of PI3Kalpha (unknown origin)

Source:: ChEMBL

Protein Target:: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1937367

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 193736310.

Inhibition of PI3Kalpha in human MCF7 cells assessed as decrease in PI3Kalpha gene expression by measuring relative expression ratio at 0.8 uM incubated for 24 hrs by fluorescence quantitative PCR assay relative to control

Source:: ChEMBL

Protein Target:: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

Assay data:1 Tested

AID:: 1937363

Summary PubMed Citation Related BioAssays by Target

Select item 193736211.

Inhibition of PI3Kalpha in human MCF7 cells assessed as decrease in PI3Kalpha gene expression incubated for 24 hrs by fluorescence quantitative PCR assay

Source:: ChEMBL

Protein Target:: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

Assay data:1 Tested

AID:: 1937362

Summary PubMed Citation Related BioAssays by Target

Select item 193734112.

Inhibition of PI3Kalpha (unknown origin) by kinase-glo luminescent assay

Source:: ChEMBL

Protein Target:: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

Assay data:9 Active, 3 Activity ≤ 1 µM, 18 Tested

AID:: 1937341

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 193733913.

Inhibition of PI3Kalpha (unknown origin) at 1 uM by kinase-glo luminescent assay relative to control

Source:: ChEMBL

Protein Target:: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

Assay data:18 Tested

AID:: 1937339

Summary PubMed Citation Related BioAssays by Target

Select item 193488014.

Inhibition of PI3 kinase p110alpha/p85alpha (unknown origin) at 1 uM relative to control

Source:: ChEMBL

Protein Targets:: Phosphatidylinositol 3-kinase regulatory subunit alpha; ...
Total:: 2

Assay data:1 Tested

AID:: 1934880

Summary PubMed Citation Related BioAssays by Target

Select item 193407615.

Inhibition of PI3Kalpha (unknown origin)

Source:: ChEMBL

Protein Target:: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

Assay data:4 Active, 4 Activity ≤ 1 µM, 5 Tested

AID:: 1934076

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 192891916.

Inhibition of PI3Kalpha (unknown origin) incubated for 90 mins by [gamma-33P]-ATP based scintillation counting method

Source:: ChEMBL

Protein Target:: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

Assay data:1 Active, 4 Tested

AID:: 1928919

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 192858017.

Inhibition of PIK3alpha (unknown origin) expressed in baculovirus assessed as inhibition constant using PIP2 as substrate in presence of [gamma-32P]ATP incubated for 30 mins by scintillation proximity assay

Source:: ChEMBL

Protein Target:: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1928580

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 192857318.

Inhibition of PI3Kalpha (unknown origin)

Source:: ChEMBL

Protein Target:: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1928573

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 192856819.

Inhibition of human PI3Kalpha assessed as inhibition constant

Source:: ChEMBL

Protein Target:: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1928568

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 192856020.

Inhibition of human recombinant PI3Kalpha in presence of ATP by scintillation proximity assay

Source:: ChEMBL

Protein Target:: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1928560

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

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