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Selectivity interaction (KinomeScan (DiscoverX)) EUB0000753a MAP4K5
Assay data:1 Tested
SummaryRelated BioAssays by Target
Selectivity interaction (KinomeScan (DiscoverX)) EUB0000147b MAP4K5
Inhibition of MAP4K5 (KHS1) (unknown origin) at 1 uM relative to control
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of MAP4K5 (unknown origin) assessed as residual activity at 1 uM by radiometric 33 PanQuinase assay relative to control
Inhibition of full length C-terminal nanoLuc-tagged human MAP4K5 (KHS1) expressed in HEK293 cells using NanoBRET NanoGlo substrate incubated for 2 hrs in presence of tracer K10 by NanoBRET assay
Inhibition of human MAP4K5 (KHS1) by radiometric PanQinase activity assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of human MAP4K5 (KHS1) at 1 uM by radiometric PanQinase activity assay relative to control (Rvb=50%)
Inhibition of MAP4K5 in HEK293 cells by NanoBRET assay
Inhibition of human wild type MAP4K5 assessed as remaining activity at 1 uM by MRC screening assay relative to control
Binding affinity to MAP4K5 (unknown origin) assessed as dissociation constant by competition binding assay
Assay data:1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
MAP4K3 DiscoveRx kinase panel
MAP4K5 DiscoveRx kinase panel
MAP4K5(h) Kinase panel
MAP4K3(h) Kinase panel
Inhibition of KHS (unknown origin) at 1 uM
Inhibition of GLK (unknown origin) at 1 uM
KinomeScan assay: inhibition of MAP4K5
Assay data:1 Active, 108 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
KinomeScan assay: inhibition of MAP4K3
Assay data:108 Tested
KHS1(M4K5LGY1) Takeda global kinase panel
SummaryCompounds, activity ≤ 1 µMRelated BioAssays by Target
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