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Inhibition of PDE4 from US Patent US11987556: "Dual-functional compounds and methods of use"
Assay data:6 Active, 6 Activity ≤ 1 µM, 6 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Biochemical Kinase Assay Protocol (JAK) from US Patent US20240132525: "BORON CONTAINING PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM, METHODS AND USES THEREOF"
Assay data:90 Active, 39 Activity ≤ 1 nM, 91 Activity ≤ 1 µM, 91 Tested
In vitro PDE4B Enzyme Activity Detection Assay from US Patent US20240083921: "BORATE DERIVATIVE AND USES THEREOF"
Assay data:14 Active, 12 Activity ≤ 1 nM, 14 Activity ≤ 1 µM, 14 Tested
Cross screening panel
Assay data:1 Tested
SummaryRelated BioAssays by Target
Safety47 Scan (DiscoverX - Eurofins)
Phosphodiesterase PDE4 Eurofins Panlabs panel
Panlabs assay PDE4D2
Panlabs assay PDE4C1
Panlabs assay PDE4B1
Panlabs assay PDE4A1A
3H-cAMP and 3H-cGMP Scintillation Proximity Assay (PDE4B)
PDE4D2 Eurofins SafetyScreen44 (BI)
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