Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19629251.

MAP2K1 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Dual specificity mitogen-activated protein kinase kinase 1

Assay data:1 Tested

AID:: 1962925

Summary Related BioAssays by Target

Select item 19628212.

MAP2K1 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Dual specificity mitogen-activated protein kinase kinase 1

Assay data:1 Tested

AID:: 1962821

Summary Related BioAssays by Target

Select item 19627233.

MAP2K1 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Dual specificity mitogen-activated protein kinase kinase 1

Assay data:1 Tested

AID:: 1962723

Summary Related BioAssays by Target

Select item 19626244.

MAP2K1 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Dual specificity mitogen-activated protein kinase kinase 1

Assay data:1 Tested

AID:: 1962624

Summary Related BioAssays by Target

Select item 19624215.

MAP2K2 Invitrogen Lab (UK) kinase screen (BI)

Source:: ChEMBL

Protein Target:: Dual specificity mitogen-activated protein kinase kinase 2

Assay data:1 Tested

AID:: 1962421

Summary Related BioAssays by Target

Select item 19624206.

MAP2K1 Invitrogen Lab (UK) kinase screen (BI)

Source:: ChEMBL

Protein Target:: Dual specificity mitogen-activated protein kinase kinase 1

Assay data:1 Tested

AID:: 1962420

Summary Related BioAssays by Target

Select item 19622747.

MAP2K2 Invitrogen Lab (UK) kinase screen (BI)

Source:: ChEMBL

Protein Target:: Dual specificity mitogen-activated protein kinase kinase 2

Assay data:1 Tested

AID:: 1962274

Summary Related BioAssays by Target

Select item 19622738.

MAP2K1 Invitrogen Lab (UK) kinase screen (BI)

Source:: ChEMBL

Protein Target:: Dual specificity mitogen-activated protein kinase kinase 1

Assay data:1 Tested

AID:: 1962273

Summary Related BioAssays by Target

Select item 19583729.

Inhibition of MEK1 (unknown origin) at 1 uM relative to control

Source:: ChEMBL

Protein Target:: Dual specificity mitogen-activated protein kinase kinase 1

Assay data:3 Tested

AID:: 1958372

Summary PubMed Citation Related BioAssays by Target

Select item 195649110.

Inhibition of MEK2 (unknown origin) by discoverX kinomescan assay

Source:: ChEMBL

Protein Target:: Dual specificity mitogen-activated protein kinase kinase 2

Assay data:1 Tested

AID:: 1956491

Summary PubMed Citation Related BioAssays by Target

Select item 195649011.

Inhibition of MEK1 (unknown origin) by discoverX kinomescan assay

Source:: ChEMBL

Protein Target:: Dual specificity mitogen-activated protein kinase kinase 1

Assay data:1 Tested

AID:: 1956490

Summary PubMed Citation Related BioAssays by Target

Select item 194248612.

Inhibition of human MEK2

Source:: ChEMBL

Protein Target:: Dual specificity mitogen-activated protein kinase kinase 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1942486

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 194248513.

Inhibition of human MEK1

Source:: ChEMBL

Protein Target:: Dual specificity mitogen-activated protein kinase kinase 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1942485

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 194087214.

Inhibition of MAP2K1 (unknown origin) at 1000 nM relative to control

Source:: ChEMBL

Protein Target:: Dual specificity mitogen-activated protein kinase kinase 1

Assay data:1 Tested

AID:: 1940872

Summary PubMed Citation Related BioAssays by Target

Select item 194087115.

Inhibition of MAP2K1 (unknown origin)

Source:: ChEMBL

Protein Target:: Dual specificity mitogen-activated protein kinase kinase 1

Assay data:1 Activity ≤ 1 µM, 1 Tested

AID:: 1940871

Summary Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 193485816.

Inhibition of human full length wild type MEK1 expressed in mammalian system at 1 uM by KINOMEscan analysis relative to control

Source:: ChEMBL

Protein Target:: Dual specificity mitogen-activated protein kinase kinase 1

Assay data:1 Tested

AID:: 1934858

Summary PubMed Citation Related BioAssays by Target

Select item 192938617.

Inhibition of MEK1 (unknown origin)

Source:: ChEMBL

Protein Target:: Dual specificity mitogen-activated protein kinase kinase 1

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1929386

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 192434018.

Inhibition of MEK1 (unknown origin)

Source:: ChEMBL

Protein Target:: Dual specificity mitogen-activated protein kinase kinase 1

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1924340

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 192412319.

Inhibition of MEK1 (unknown origin)

Source:: ChEMBL

Protein Target:: Dual specificity mitogen-activated protein kinase kinase 1

Assay data:1 Active, 1 Tested

AID:: 1924123

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 192275920.

Induction of MEK1/2 degradation in human A549 cells assessed as reduction in pERK1/2 levels at 1 to 30 uM incubated for 24 hrs by Western blot analysis

Source:: ChEMBL

Protein Targets:: Dual specificity mitogen-activated protein kinase kinase 1; ...
Total:: 2

Assay data:1 Active, 1 Tested

AID:: 1922759

Summary Compounds, Active PubMed Citation Related BioAssays by Target

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Target

Proteins (9)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (389)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (22)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (239)
BioAssays with the active concentration of tested reagents less than 1 micromolar

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Confirmatory (339)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

Assay Project (3)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

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Literature Extraction (1,093)
BioAssays extracted from the literature
NIH MLP (4)
BioAssays deposited by the NIH Molecular Libraries Program
Other (92)
BioAssays deposited by other experimentalists

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