Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Compound was evaluated for inhibition of rat Cacna1b in an in vitro assay with cellular components measured by membrane filtration
Assay data:1 Active, 314 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Calcium Channels Interaction from US Patent US10626144: "Peptide derivatives and uses thereof"
Assay data:26 Active, 41 Activity ≤ 1 µM, 42 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Inhibition of Cav2.2 (unknown origin) at a holding potential +10 mV at 10 uM by whole cell patch clamp electrophysiology relative to control
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of Cav2.2 (unknown origin) at a holding potential +10 mV at 30 uM by whole cell patch clamp electrophysiology relative to control
Inhibition of endogenous human CaV2.2 in human SH-SY5Y cells in presence of nifedipine by Calcium 4 dye based calcium influx fluorescence-imaging assay
Assay data:4 Active, 14 Tested
Inhibition of human Cav2.2
Assay data:1 Active, 1 Tested
CA+/N/RA Eurofins SafetyScreen44 (BI)
SummaryRelated BioAssays by Target
Displacement of [125I]omegaCTx-GVIA from N-type calcium channel (unknown origin) at 10 uM relative to control
Patch Clamp/Inhibition Assay from US Patent US9447029: "Fluorinated arylalkylaminocarboxamide derivatives"
Assay data:10 Active, 8 Activity ≤ 1 µM, 10 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Functional Drug Screening System (FDSS) from US Patent US9434693: "Substituted pyrazoles as N-type calcium channel blockers"
Assay data:45 Active, 45 Activity ≤ 1 µM, 45 Tested
High-Throughput Cav2.2/Kir2.3 T-Type Fluorescent Assay from US Patent US9688615: "Benzimidazole inhibitors of the sodium channel"
Assay data:17 Active, 99 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Target
Ca2+ channel (N) CEREP ligand profiling
CA+/N/RA Eurofins-Panlabs selectivity data (BI)
CA+/N/R Cerep selectivity data (BI)
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on