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Dopamine D3 Eurofins Panlabs panel
Assay data:1 Tested
SummaryRelated BioAssays by Target
Binding affinity towards human DRD3 in an in vitro assay with cellular components measured by scintillation counting
Assay data:176 Active, 1 Activity ≤ 1 nM, 87 Activity ≤ 1 µM, 1215 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Assay data:142 Active, 80 Activity ≤ 1 µM, 896 Tested
Displacement of [3H]methylspiperone from human D3 receptor stably expressed in HEK293T cells by Cheng-Prusoff equation analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Displacement of [3H]N-methylspiperone from D3 receptor in HEK293 cell membrane assessed as inhibition constant
Assay data:7 Active, 5 Activity ≤ 1 µM, 7 Tested
Agonist activity at human D3 receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding by measuring maximum efficacy by Perkin elmer analysis relative to control
Assay data:9 Tested
SummaryPubMed CitationRelated BioAssays by Target
Agonist activity at human D3 receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding by Perkin elmer analysis
Assay data:9 Active, 4 Activity ≤ 1 nM, 9 Activity ≤ 1 µM, 9 Tested
Displacement of [3H]-spiroperidol from rat D3 receptor expressed in HEK293 cells assessed as inhibition constant by Cheng-Prusoff equation analysis
Assay data:9 Active, 9 Activity ≤ 1 µM, 9 Tested
Binding affinity to human D3 receptor expressed in CHO cells assessed as inhibition constant by scintillation counting method
Assay data:7 Active, 4 Activity ≤ 1 nM, 12 Activity ≤ 1 µM, 15 Tested
Inhibition of human D3 receptor expressed in CHO cells by scintillation counting method relative to control
Inhibition of human D3 receptor expressed in CHO cells at 1 uM by scintillation counting method relative to control
Assay data:6 Tested
Inhibition of human D3 receptor expressed in CHO cells at 10 uM by scintillation counting method relative to control
Assay data:15 Tested
Inhibition of human D3 receptor expressed in CHO cells assessed as inhibition constant by scintillation counting method
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
Partial agonist activity at human D3 receptor expressed in HEK293T cells assessed as inhibition of forskolin-induced cAMP production incubated for 1 hr by HTRF analysis relative to control
Assay data:23 Tested
Partial agonist activity at human D3 receptor expressed in HEK293T cells assessed as inhibition of forskolin-induced cAMP production incubated for 1 hr by HTRF analysis
Assay data:18 Active, 7 Activity ≤ 1 µM, 23 Tested
Partial agonist activity at human D3 receptor assessed as inhibition constant
Assay data:5 Active, 2 Activity ≤ 1 nM, 5 Activity ≤ 1 µM, 5 Tested
Agonist activity at D3R (unknown origin)
Displacement of [3H]-spiperone from human D3 receptor expressed in CCCL-1 cells assessed as inhibition constant
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Displacement of [3H]-spiperone from human D3 receptor expressed in CHO cells assessed as inhibition constant
Binding affinity to human D3R assessed as inhibition constant by Cheng-Prusoff equation analysis
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