Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
hKAT-I Activity Assay from Article 10.1021/jm9000874: "Structural insight into the inhibition of human kynurenine aminotransferase I/glutamine transaminase K."
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of KAT1 (unknown origin)
Assay data:1 Tested
Inhibition of KAT1 (unknown origin) at 100 uM
Human L-Cysteine:2-oxoglutarate aminotransferase (Hydrogen sulphide synthesis)
Assay data:1 Active, 1 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Inhibition of human KAT1 using L-kynurenine as substrate measured after 16 hrs by SpectraMax plate reader analysis
Assay data:1 Active, 4 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of human KAT1
Ratio of compound IC50 to indole-3-propionic acid IC50 for human recombinant KAT1
Assay data:3 Tested
Inhibition of human recombinant KAT1 after 20 mins by RP-HPLC analysis
Assay data:12 Tested
Inhibition of human recombinant MBP-KAT1 expressed in HEK293 cells assessed as conversion of L-kynurenine to kynurenic acid after 1 hr
Inhibition of KAT1 in human prefrontal cortex homogenates
Inhibition of human recombinant KAT1 expressed in Sf9 cells
Assay data:4 Active, 6 Tested
Inhibition of human recombinant KAT1 expressed in Sf9 cells assessed as decrease in enzyme activity at 25 % ligand concentration
Ratio of Vmax and Km for elimination of conjugates by rat renal cytosol
Assay data:14 Tested
Apparent enzyme kinetic parameter (Vmax) was determined for the beta -elimination by rat renal cytosol
Specific activity against beta-elimination reaction by rat renal cytosolic beta-lyase after incubation with 0.2 mg of protein/mL for 10 min at 37 degree C using 1 mM substrate conc.
Assay data:23 Tested
Apparent enzyme kinetic parameter (Km) was determined for the beta -elimination by rat renal cytosol
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on