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Assay for Inhibition of Compounds Provided in the Present Application on CYP Enzymes from US Patent US20240226107: "UBIQUITIN-SPECIFIC PROTEASE 1 (USP1) INHIBITOR"
Assay data:1 Active, 2 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Target
The Inhibitory Effect of the Compound on the Activity of Human Liver Microsomal Cytochrome P450 Isoenzymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP3A4) from US Patent US12030897: "Pyrrolo[2,1-f][1,2,4]triazine derivatives serving as selective HER2 inhibitors and application thereof"
Assay data:1 Tested
SummaryRelated BioAssays by DepositorRelated BioAssays by Target
Evaluation of A2a Receptor Binding Affinity from US Patent US20240217978: "COMPOUND AS ADENOSINE A2a RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITION COMPRISING SAME"
Assay data:395 Active, 50 Activity ≤ 1 nM, 388 Activity ≤ 1 µM, 396 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
hERG Inhibition Assay from US Patent US20240216357: "POLYCYCLIC COMPOUND AND APPLICATION THEREOF"
Assay data:23 Active, 41 Tested
CYP450 Enzyme Inhibition Assay from US Patent US20240216357: "POLYCYCLIC COMPOUND AND APPLICATION THEREOF"
Assay data:10 Active, 23 Tested
Receptor Binding Assay from US Patent US12023331: "Methods"
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
CYP Enzyme Single Point Inhibition Assay from US Patent US20240208981: "NITROGEN-CONTAINING HETEROCYCLIC POLYCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF"
Assay data:1 Active, 4 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
hERG Qpatch Assay from US Patent US20240208953: ""Cyclopenta[c]pyrrol Negative Allosteric Modulators of NR2B""
Assay data:20 Active, 4 Activity ≤ 1 µM, 25 Tested
CYP450 Enzyme Inhibition Assay from US Patent US20240208932: "ARYLAMINO DERIVATIVE ESTROGEN RECEPTOR MODULATOR AND USE THEREOF"
Assay data:4 Tested
SummaryRelated BioAssays by Target
hERG Qpatch Assay Protocol from US Patent US20240199576: "NOVEL CYCLOPENTA[C]PYRROL NEGATIVE ALLOSTERIC MODULATORS OF NR2B"
Assay data:3 Active, 5 Tested
hEP4 cAMP Assay from US Patent US12011444: "N-substituted indole derivatives as PGE2 receptor modulators"
Assay data:1074 Active, 7 Activity ≤ 1 nM, 1074 Activity ≤ 1 µM, 1074 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
[3H]DA and [3H]5-HT Uptake Assay from US Patent US11999676: "Vesicular monoamine transporter-2 ligands and their use in the treatment of psychostimulant abuse"
Assay data:90 Active, 90 Activity ≤ 1 µM, 91 Tested
Inhibition of Cytochrome P450 Oxidase from US Patent US20240158438: "POLYPEPTIDE COMPOUND AND APPLICATION THEREOF"
Assay data:2 Active, 31 Tested
CYP Enzyme Inhibition Assay from US Patent US11981669: "1,7-naphthyridine derivative and preparation method and use therefor"
Assay data:8 Tested
hERG Channel Inhibitory Activity Assay from US Patent US20240150370: "BICYCLIC PYRIDINE DERIVATIVE"
Assay data:2 Active, 39 Tested
Adenosine Receptor Activity Assay from US Patent US11974991: "Adenosine receptor activity of methyl/ethyl 3-(substituted benzoyl)-6,8-dimethylindolizine-2-substituted-1-carboxylates"
Assay data:11 Active, 5 Activity ≤ 1 µM, 13 Tested
CYP Enzyme Inhibitory Activity IC50 Assay from US Patent US20240124479: "PYRIMIDINE CARBOXAMIDE COMPOUND AND USE THEREOF"
Affinity of the Compounds of the Present Invention for Dopamine D2 Receptors from US Patent US20240124456: "AZA-ERGOLINE DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF"
Assay data:32 Active, 1 Activity ≤ 1 nM, 29 Activity ≤ 1 µM, 32 Tested
Enzymatic Activity of CYP2C9, CYP2D6, and CYP3A4 from US Patent US20240124454: "TRICYCLIC COMPOUND AND USE THEREOF"
Assay data:10 Tested
CYP inhibitio from US Patent US20240124434: "ATF6 INHIBITORS AND USES THEREOF"
Assay data:10 Active, 3 Activity ≤ 1 µM, 17 Tested
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