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ALPHA Screen Assay with TLX LBD from US Patent US20240067625: "SMALL-MOLECULE MODULATORS OF THE ORPHAN NUCLEAR RECEPTOR TLX"
Assay data:43 Active, 41 Activity ≤ 1 nM, 41 Activity ≤ 1 µM, 43 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Luciferase assay from US Patent US11912681: "Crystalline and salt forms of PPAR agonist compounds"
Assay data:2 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested
THR/RXR Heterodimer Assay for Thyroid Hormone Receptor Agonist Screening from US Patent US20240059682: "THYROID HORMONE RECEPTOR BETA AGONIST COMPOUNDS"
Assay data:26 Active, 25 Activity ≤ 1 µM, 26 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) Assay for Thyroid Hormone Receptor Agonist Screening from US Patent US20240059682: "THYROID HORMONE RECEPTOR BETA AGONIST COMPOUNDS"
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
THR Reporter Gene Method from US Patent US20240059676: "THYROID HORMONE RECEPTOR b SELECTIVE AGONIST COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF"
Assay data:32 Active, 21 Activity ≤ 1 µM, 38 Tested
MCF-7 Cell Growth Study from US Patent US20240043442: "SELECTIVE ESTROGEN RECEPTOR DEGRADERS AND USES THEREOF"
Assay data:50 Active, 30 Activity ≤ 1 nM, 50 Activity ≤ 1 µM, 50 Tested
Human PPARalpha Reporter Assay from US Patent US20240041837: "TRIAZOLONE COMPOUNDS AND USES THEREOF"
Assay data:29 Active, 24 Activity ≤ 1 µM, 29 Tested
Cross screening panel
Assay data:1 Tested
SummaryRelated BioAssays by Target
Safety47 Scan (DiscoverX - Eurofins)
Progesterone PR-B Eurofins Panlabs panel
Glucocorticoid Eurofins Panlabs panel
Estrogen Eralpha Eurofins Panlabs panel
Androgen (Testosterone) Eurofins Panlabs panel
GCORTICOID/H Eurofins SafetyScreen44 (BI)
ANDROGEN/H Eurofins SafetyScreen44 (BI)
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