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hERG Assay from US Patent US11970463: "Compounds and their use"
Assay data:1 Active, 35 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
GABAA (α1β2γ2) Receptor Current using Patch-Clamp Technique from US Patent US20240132445: "PHENOL DERIVATIVE AND APPLICATION THEREOF IN MEDICAMENTS"
Assay data:1 Active, 2 Tested
assay on hold
Summary
In Vitro Activity Assay from US Patent US11944616: "Dizocilpine derivatives as peripheral NMDA receptor antagonists"
Assay data:10 Active, 9 Activity ≤ 1 µM, 10 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
CYP1A2 Inhibition Assay from US Patent US11938127: "Methods and compositions relating to steroid hormone receptor-dependent proliferative disorders"
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Mu-Opioid Receptor Activity Assay from US Patent US20240092802: "MU-OPIOID RECEPTOR AGONISTS AND USES THEREFOR"
Assay data:68 Active, 18 Activity ≤ 1 µM, 77 Tested
Adenosine Receptor Time-Resolved Fluorescence Resonance Energy Transfer (TRFRET) Binding Assay from US Patent US20240083904: "ANTAGONISTS OF THE ADENOSINE A2A RECEPTOR"
Assay data:13 Active, 10 Activity ≤ 1 nM, 13 Activity ≤ 1 µM, 13 Tested
Measurement of A2A or A2B Binding Affinity Using Radioligand Binding from US Patent US20240076297: "ADENOSINE A2A AND A2B RECEPTOR DUAL ANTAGONISTS FOR IMMUNO-ONCOLOGY"
Assay data:28 Active, 3 Activity ≤ 1 nM, 28 Activity ≤ 1 µM, 28 Tested
Measurement of A2A or A2B Binding Affinity Using SPA from US Patent US20240076297: "ADENOSINE A2A AND A2B RECEPTOR DUAL ANTAGONISTS FOR IMMUNO-ONCOLOGY"
Assay data:18 Active, 15 Activity ≤ 1 µM, 18 Tested
Patch Clamp Electrophysiology from US Patent US11912737: "19-nor neuroactive steroids and methods of use thereof"
Assay data:2 Active, 3 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Target
BCA Protein Assay Kit from US Patent US11912716: "Compound, preparation method and use thereof"
Assay data:4 Active, 3 Activity ≤ 1 µM, 4 Tested
hERG Channel Activity from US Patent US11912693: "Compounds for modulating S1P1 activity and methods of using the same"
Assay data:1 Active, 1 Activity ≤ 1 µM, 11 Tested
Experimental Evaluation of the In Vitro Inhibitory Effect (IC50) of hERG from US Patent US11912663: "Multi-targeted tyrosine kinase inhibitors and their pharmaceutical uses"
Assay data:15 Tested
SummaryRelated BioAssays by DepositorRelated BioAssays by Target
Binding Assay from US Patent US20240043418: "1,3-DIHYDRO-2H-PYRROLO[3,4-C]PYRIDINE DERIVATIVES AS GABAA A5 RECEPTOR MODULATORS"
Assay data:3 Active, 1 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 3 Tested
Determination of the Effect of a SERCA Agonist on the Reduction of ER Stress from US Patent US11890279: "Quinolines that modulate SERCA and their use for treating disease"
Assay data:11 Tested
Cross screening panel
Assay data:1 Tested
SummaryRelated BioAssays by Target
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