Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19634901.

CDK2/Cyclin E1 HTRF Enzyme Activity Assay from US Patent US11919904: "Sulfonylamide compounds as CDK2 inhibitors"

Source:: BindingDB

Protein Targets:: Cyclin-dependent kinase 2; ...
Total:: 2

Assay data:14 Active, 14 Activity ≤ 1 µM, 14 Tested

AID:: 1963490

Summary Related BioAssays by Target

Select item 19634852.

In Vitro Test of Activities of Jak1, Jak2, Jak3, Tyk2 Kinases from US Patent US11919896: "[1,2,4]triazolo[1,5-a]pyridine compound as JAK inhibitor and use thereof"

Source:: BindingDB

Protein Targets:: Tyrosine-protein kinase JAK1; ...
Total:: 1

Assay data:34 Active, 34 Activity ≤ 1 µM, 34 Tested

AID:: 1963485

Summary Related BioAssays by Target

Select item 19634813.

In Vitro JAK Kinase Assay from US Patent US11918581: "Combination therapy comprising JAK pathway inhibitor and rock inhibitor"

Source:: BindingDB

Protein Targets:: Tyrosine-protein kinase JAK1; ...
Total:: 1

Assay data:26 Active, 26 Activity ≤ 1 µM, 26 Tested

AID:: 1963481

Summary Related BioAssays by Target

Select item 19634534.

FRET based assay from US Patent US11912660: "S6K1 protein kinase inhibitors as cancer therapeutics"

Source:: BindingDB

Protein Targets:: Ribosomal protein S6 kinase beta-1; ...
Total:: 1

Assay data:2 Active, 3 Tested

AID:: 1963453

Summary Related BioAssays by Target

Select item 19634035.

In Vitro JAK Kinase Assay from US Patent US20240058343: "TREATMENT OF URTICARIA USING JAK INHIBITORS"

Source:: BindingDB

Protein Targets:: Tyrosine-protein kinase JAK1; ...
Total:: 1

Assay data:26 Active, 26 Activity ≤ 1 µM, 26 Tested

AID:: 1963403

Summary Related BioAssays by Target

Select item 19633516.

TBD from US Patent US20240034743: "TRICYCLIC COMPOUNDS AS EGFR INHIBITORS"

Source:: BindingDB

Protein Targets:: Epidermal growth factor receptor; ...
Total:: 1

Assay data:135 Active, 118 Activity ≤ 1 nM, 137 Activity ≤ 1 µM, 137 Tested

AID:: 1963351

Summary Related BioAssays by Target

Select item 19633507.

TBD from US Patent US20240034743: "TRICYCLIC COMPOUNDS AS EGFR INHIBITORS"

Source:: BindingDB

Protein Targets:: Epidermal growth factor receptor; ...
Total:: 1

Assay data:133 Active, 31 Activity ≤ 1 nM, 137 Activity ≤ 1 µM, 137 Tested

AID:: 1963350

Summary Related BioAssays by Target

Select item 19633448.

CDK2/Cyclin E1 Full length ADP-Glo Kinase Assay from US Patent US20240034731: "AZA-QUINAZOLINE COMPOUNDS AND METHODS OF USE"

Source:: BindingDB

Protein Targets:: Cyclin-dependent kinase 2; ...
Total:: 2

Assay data:95 Active, 92 Activity ≤ 1 µM, 97 Tested

AID:: 1963344

Summary Related BioAssays by Target

Select item 19633439.

CDK1/Cyclin B1 ADP-Glo Kinase Assay from US Patent US20240034731: "AZA-QUINAZOLINE COMPOUNDS AND METHODS OF USE"

Source:: BindingDB

Protein Targets:: Cyclin-dependent kinase 1; ...
Total:: 2

Assay data:75 Active, 1 Activity ≤ 1 nM, 52 Activity ≤ 1 µM, 99 Tested

AID:: 1963343

Summary Related BioAssays by Target

Select item 196333610.

Assay for Inhibition of CDK2/CyclinE1 from US Patent US20240033264: "CDK INHIBITORS"

Source:: BindingDB

Protein Targets:: Cyclin-dependent kinase 2; ...
Total:: 2

Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested

AID:: 1963336

Summary Related BioAssays by Target

Select item 196312111.

NanoBRET assay (JAK1, SGC Frankfurt)

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase JAK1

Assay data:2 Tested

AID:: 1963121

Summary Related BioAssays by Target

Select item 196311612.

NanoBRET (AKT3)

Source:: ChEMBL

Protein Target:: RAC-gamma serine/threonine-protein kinase

Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 1963116

Summary Related BioAssays by Target

Select item 196295013.

AKT3 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: RAC-gamma serine/threonine-protein kinase

Assay data:1 Tested

AID:: 1962950

Summary Related BioAssays by Target

Select item 196293314.

MAPK9 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase 9

Assay data:1 Tested

AID:: 1962933

Summary Related BioAssays by Target

Select item 196293215.

MAPK8 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase 8

Assay data:1 Tested

AID:: 1962932

Summary Related BioAssays by Target

Select item 196293116.

MAPK14 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase 14

Assay data:1 Tested

AID:: 1962931

Summary Related BioAssays by Target

Select item 196293017.

MAPK13 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase 13

Assay data:1 Tested

AID:: 1962930

Summary Related BioAssays by Target

Select item 196292918.

MAPK10 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase 10

Assay data:1 Tested

AID:: 1962929

Summary Related BioAssays by Target

Select item 196292719.

MAP2K6 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Dual specificity mitogen-activated protein kinase kinase 6

Assay data:1 Tested

AID:: 1962927

Summary Related BioAssays by Target

Select item 196292520.

MAP2K1 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Dual specificity mitogen-activated protein kinase kinase 1

Assay data:1 Tested

AID:: 1962925

Summary Related BioAssays by Target

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Proteins (162)
BioAssays with protein sequences specified as targets

BioActivity

Chemical Probes (2)
BioAssays with compounds reported as validated chemical probes

Active Compounds (11,898)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (1,455)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (8,543)
BioAssays with the active concentration of tested reagents less than 1 micromolar

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Summary (5)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (12,855)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (15)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose

Assay Project (91)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

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Literature Extraction (29,651)
BioAssays extracted from the literature
NIH MLP (104)
BioAssays deposited by the NIH Molecular Libraries Program
Other (4,784)
BioAssays deposited by other experimentalists

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