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Late stage assay provider assay for inhibitors of SRC-1 and SRC-3: HeLa Cell growth comparison in SRC-3 wild type and SRC-3 knockout (zinc finger nuclease) conditions
Assay data:6 Active, 51 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Late stage assay provider assay for the probe development effort to identify SRC-3 cellular protein concentration
Assay data:6 Active, 2 Activity ≤ 1 µM, 6 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Late stage Counterscreen for the probe development effort to identify inhibitors of the Steroid Receptor Coactivator 1 (SRC1; NCOA1): Luminescence-based cell-based dose response assay to identify inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3)
Assay data:2 Active, 1 Activity ≤ 1 µM, 3 Tested
Late stage assay for the probe development effort to identify inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3): Luminescence-based cell-based dose response assay for SRC3 inhibitors
Assay data:6 Active, 8 Tested
Counterscreen for inhibitors of the Steroid Receptor Coactivator 1 (SRC1; NCOA1): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3)
Assay data:178 Active, 15 Activity ≤ 1 µM, 240 Tested
Luminescence-based cell-based high throughput dose response assay for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3)
Assay data:119 Active, 4 Activity ≤ 1 µM, 229 Tested
Luminescence-based cell-based high throughput confirmation assay for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3)
Assay data:864 Active, 2301 Tested
Summary of the probe development efforts to identify inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3)
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3)
Assay data:621 Active, 359484 Tested
Summary assay for compounds that decrease p/CIP protein stability
Fluorescence for the identification of compounds that decrease p/CIP protein stability
Assay data:36 Active, 292483 Tested
Summary of probe development efforts to identify agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPAR gamma)
TR-FRET dose response biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPAR gamma): non-selective agonists
Assay data:11 Active, 400 Tested
Dose response biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)
Assay data:6 Active, 349 Tested
Confirmation biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)
Assay data:230 Active, 794 Tested
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)
Assay data:390 Active, 99367 Tested
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)
Assay data:519 Active, 196256 Tested
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