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assay on hold
Summary
In Vitro Activity Assay from US Patent US11944616: "Dizocilpine derivatives as peripheral NMDA receptor antagonists"
Assay data:10 Active, 9 Activity ≤ 1 µM, 10 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Mu-Opioid Receptor Activity Assay from US Patent US20240092802: "MU-OPIOID RECEPTOR AGONISTS AND USES THEREFOR"
Assay data:68 Active, 18 Activity ≤ 1 µM, 77 Tested
In vitro PDE4B Enzyme Activity Detection Assay from US Patent US20240083921: "BORATE DERIVATIVE AND USES THEREOF"
Assay data:14 Active, 12 Activity ≤ 1 nM, 14 Activity ≤ 1 µM, 14 Tested
Adenosine Receptor Time-Resolved Fluorescence Resonance Energy Transfer (TRFRET) Binding Assay from US Patent US20240083904: "ANTAGONISTS OF THE ADENOSINE A2A RECEPTOR"
Assay data:13 Active, 10 Activity ≤ 1 nM, 13 Activity ≤ 1 µM, 13 Tested
Measurement of A2A or A2B Binding Affinity Using Radioligand Binding from US Patent US20240076297: "ADENOSINE A2A AND A2B RECEPTOR DUAL ANTAGONISTS FOR IMMUNO-ONCOLOGY"
Assay data:28 Active, 3 Activity ≤ 1 nM, 28 Activity ≤ 1 µM, 28 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Measurement of A2A or A2B Binding Affinity Using SPA from US Patent US20240076297: "ADENOSINE A2A AND A2B RECEPTOR DUAL ANTAGONISTS FOR IMMUNO-ONCOLOGY"
Assay data:18 Active, 15 Activity ≤ 1 µM, 18 Tested
BCA Protein Assay Kit from US Patent US11912716: "Compound, preparation method and use thereof"
Assay data:4 Active, 3 Activity ≤ 1 µM, 4 Tested
hERG Channel Activity from US Patent US11912693: "Compounds for modulating S1P1 activity and methods of using the same"
Assay data:1 Active, 1 Activity ≤ 1 µM, 11 Tested
Experimental Evaluation of the In Vitro Inhibitory Effect (IC50) of hERG from US Patent US11912663: "Multi-targeted tyrosine kinase inhibitors and their pharmaceutical uses"
Assay data:15 Tested
SummaryRelated BioAssays by DepositorRelated BioAssays by Target
MCF-7 Cell Growth Study from US Patent US20240043442: "SELECTIVE ESTROGEN RECEPTOR DEGRADERS AND USES THEREOF"
Assay data:50 Active, 30 Activity ≤ 1 nM, 50 Activity ≤ 1 µM, 50 Tested
Determination of the Effect of a SERCA Agonist on the Reduction of ER Stress from US Patent US11890279: "Quinolines that modulate SERCA and their use for treating disease"
Assay data:11 Tested
Human P2X7 Channel Calcium-Influx Assay from US Patent US20240034737: "Heterocyclic Derivatives as P2X7 Receptor Antagonists"
Assay data:103 Active, 103 Activity ≤ 1 µM, 103 Tested
Cross screening panel
Assay data:1 Tested
SummaryRelated BioAssays by Target
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