Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
assay on hold
Summary
Kinase Assay from US Patent US20240199649: "4-AMINOPYRROLO[2,1-F][1,2,4]TRIAZINES AND PREPARATION AND USES THEREOF"
Assay data:158 Active, 42 Activity ≤ 1 nM, 157 Activity ≤ 1 µM, 158 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Homogeneous Time-Resolved Fluorescence (HTRF) from US Patent US20240199625: "BICYCLIC HETEROCYCLIC FGFR4 INHIBITOR, PHARMACEUTICAL COMPOSITION AND PREPARATION COMPRISING SAME, AND APPLICATION THEREOF"
Assay data:8 Active, 3 Activity ≤ 1 nM, 8 Activity ≤ 1 µM, 8 Tested
SHP2 Allosteric Inhibition Assay from US Patent US20240199616: "BICYCLIC COMPOUNDS AS ALLOSTERIC SHP2 INHIBITORS"
Assay data:5 Active, 4 Activity ≤ 1 µM, 5 Tested
Inhibition of auto-phosphorylation of recombinant human NF-kappaB-inducing kinase (NIK/MAP3K14) activity (AlphaScreen) from US Patent US20240199605: "SMALL MOLECULAR INHIBITORS OF NF-kB INDUCING KINASE"
Assay data:298 Active, 112 Activity ≤ 1 nM, 280 Activity ≤ 1 µM, 302 Tested
Evaluation of Enzyme Activity from US Patent US20240199571: "THIOPHENE COMPOUND AND APPLICATION THEREOF"
Assay data:88 Active, 88 Activity ≤ 1 µM, 88 Tested
ADP-Glo Assay Promega from US Patent US20240199561: "INHIBITORS OF DYRK AND PIM"
Assay data:17 Active, 17 Activity ≤ 1 µM, 17 Tested
Phosphatase (PTPase) Assay from US Patent US20240199525: "SHP2-Targeting Small Molecules For Use As Anti-Cancer Agents"
Assay data:6 Active, 2 Activity ≤ 1 µM, 10 Tested
Surface Plasmon Resonance Assay from US Patent US20240197735: "METHODS AND COMPOSITIONS COMPRISING A BRAF INHIBITOR AND A PD-1 BINDING ANTAGONIST"
Assay data:4 Active, 2 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 4 Tested
Biochemical Assay from US Patent US20240182487: "MACROCYCLES AND THEIR USE"
Assay data:40 Active, 3 Activity ≤ 1 nM, 40 Activity ≤ 1 µM, 42 Tested
Biological Assay from US Patent US20240182466: "A Crystal Form of a Fluorine-substituted Pyridopyrazole Compound and a Preparation Method Thereof"
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Biochemical Assay from US Patent US20240180886: "INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE"
Assay data:51 Active, 5 Activity ≤ 1 nM, 51 Activity ≤ 1 µM, 52 Tested
HPP Tautomerase Assay from US Patent US11999723: "Pyrazole-containing macrophage migration inhibitory factor inhibitors"
Assay data:44 Active, 20 Activity ≤ 1 µM, 53 Tested
HTRF Assay from US Patent US20240174674: "NITROGEN-CONTAINING POLYCYCLIC FUSED RING COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF"
Assay data:108 Active, 14 Activity ≤ 1 nM, 108 Activity ≤ 1 µM, 108 Tested
Measurement of FXIa Inhibition from US Patent US20240174633: "CRYSTALLINE FORMS OF (4S)-24-CHLORO-4-ETHYL-73-FLUORO-35-METHOXY-32,5-DIOXO-14-(TRIFLUORO-METHYL)-32H-6-AZA-3(4,1)-PYRIDINA-1(1)-[1,2,3]TRIAZOLA-2(1,2),7(1)-DIBENZENAHEPTAPHANE-74-CARBOXAMIDE"
Kinase Assay from US Patent US20240174621: "METHYLQUINAZOLINONE DERIVATIVES"
Assay data:5 Active, 3 Activity ≤ 1 nM, 5 Activity ≤ 1 µM, 5 Tested
Inhibition Tests on JAK-1, JAK-2 and JAK-3 Kinases from US Patent US11993603: "Preparation for 6-amino-1H-pyrazolo[3,4-d]pyrimidine-based JAK kinase inhibitor and application thereof"
Assay data:28 Active, 11 Activity ≤ 1 nM, 28 Activity ≤ 1 µM, 28 Tested
Q46 Radioligand Binding Assay from US Patent US11992535: "Compounds and probes for imaging huntingtin protein"
Assay data:87 Active, 87 Activity ≤ 1 µM, 87 Tested
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on