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Protein binding in mouse plasma after 6 hrs by equilibrium dialysis method
Assay data:2 Tested
SummaryPubMed Citation
Protein binding in human plasma after 6 hrs by equilibrium dialysis method
Assay data:6 Tested
Inhibition of human ERG expressed in HEK293 cells at 30 uM by patch clamp assay
Assay data:19 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of human ERG expressed in HEK293 cells at 3 uM by patch clamp assay
Lipophilicity, log D of the compound at pH 7.4
Assay data:14 Tested
Dissociation constant, pKa of the compound
Cytotoxicity against human HCT116 cells by Alamar blue assay
Assay data:32 Active, 30 Activity ≤ 1 µM, 34 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Binding affinity to Hsp90 N-terminal ATPase domain by isothermal titration calorimetry assay
Assay data:34 Active, 14 Activity ≤ 1 nM, 33 Activity ≤ 1 µM, 34 Tested
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