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Potentiation of colistin-induced antibacterial activity against colistin resistant Klebsiella pneumoniae B9 assessed as colistin MIC at 5 uM incubated for 16 hrs by broth microdilution method
Assay data:30 Tested
SummaryPubMed Citation
Antibacterial activity against Klebsiella pneumoniae B9 assessed as inhibition of bacterial growth incubated for 16 hrs by broth microdilution method
Assay data:31 Tested
Inhibition of Aurora C (unknown origin)
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of Aurora B (unknown origin)
Assay data:2 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Antiproliferative activity against human TT cells assessed as cell growth inhibition measured after 48 hrs by Cell titer-Glo assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed Citation
Inhibition of Aurora A (unknown origin)
Assay data:2 Active, 1 Activity ≤ 1 µM, 3 Tested
Inhibition of porcine brain GSK-3alpha/beta incubated for 30 mins in presence of [33p]-gamma ATP by scintillation counter analysis
Assay data:3 Active, 3 Activity ≤ 1 µM, 5 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Inhibition of GST-fused CDK5/p25 (unknown origin)
Assay data:3 Active, 2 Activity ≤ 1 µM, 5 Tested
Inhibition of starfish oocyte CDK1/Cyclin B using histone H1 as substrate incubated for 10 mins in presence of [gamma-32P]ATP by scintillation counter analysis
Assay data:4 Active, 3 Activity ≤ 1 µM, 6 Tested
Cytotoxicity against human HepG2 cells assessed as cell growth inhibition after 24 hrs by alamar blue assay
Assay data:25 Active, 1 Activity ≤ 1 µM, 60 Tested
Cytotoxicity against human KCL22 cells harboring ABL1 T315I mutant assessed as reduction in cell viability at 1 uM after 48 hrs by MTS assay
Assay data:62 Tested
Cytotoxicity against human KCL22 cells assessed as reduction in cell viability at 1 uM after 48 hrs by MTS assay
Antiproliferative activity against apoptosis sensitive human MCF7 cells after 72 hrs by MTT assay
Assay data:5 Active, 2 Activity ≤ 1 µM, 21 Tested
Antiproliferative activity against apoptosis sensitive human PC3 cells after 72 hrs by MTT assay
Assay data:3 Active, 1 Activity ≤ 1 µM, 21 Tested
Antiproliferative activity against apoptosis sensitive mouse B16F10 cells after 72 hrs by MTT assay
Assay data:12 Active, 5 Activity ≤ 1 µM, 21 Tested
Antiproliferative activity against apoptosis sensitive human Hs683 cells after 72 hrs by MTT assay
Assay data:6 Active, 1 Activity ≤ 1 µM, 21 Tested
Antiproliferative activity against apoptosis resistant human SK-MEL-28 cells after 72 hrs by MTT assay
Assay data:2 Active, 1 Activity ≤ 1 µM, 21 Tested
Antiproliferative activity against apoptosis resistant human OE21 cells after 72 hrs by MTT assay
Assay data:7 Active, 1 Activity ≤ 1 µM, 21 Tested
Antiproliferative activity against apoptosis resistant human A549 cells after 72 hrs by MTT assay
Antiproliferative activity against apoptosis resistant human U373 cells after 72 hrs by MTT assay
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