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Antileishmanial activity against promastigote Leishmania donovani
Assay data:10 Active, 4 Activity ≤ 1 µM, 14 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Antileishmanial activity against promastigote Leishmania major
Assay data:9 Active, 5 Activity ≤ 1 µM, 14 Tested
Selectivity index, ratio of IC50 for recombinant human DHFR to IC50 for Leishmania major DHFR in promastigote stage Leishmania major
Assay data:10 Tested
SummaryPubMed Citation
Inhibition of recombinant human DHFR measured by spectrophotometric method
Assay data:11 Active, 8 Activity ≤ 1 µM, 15 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of Leishmania major DHFR in promastigote stage Leishmania major using dihydrofolic acid as substrate in presence of NADPH measured after 5 days by spectrophotometric method
Assay data:12 Active, 10 Activity ≤ 1 µM, 14 Tested
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