Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Cytotoxicity against human HEK293 cells assessed as cell viability at 50 uM measured after 24 hrs by Alamar Blue assay
Assay data:15 Tested
SummaryPubMed Citation
Inhibition of HDAC1 in human MV4-11 cells assessed as accumulation of acetylated histone H3 at 2 to 15 uM measured by immunoblotting method
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Induction of autophagy in human MV4-11 cells assessed as increase in autophagic vesicles at 2 to 15 uM measured by cyto-ID green staining based flow cytometry assay
Assay data:2 Active, 2 Tested
SummaryCompounds, ActivePubMed Citation
Induction of autophagy in human SK-N-BE(2)-C cells assessed as increase in lysosomal compartment measured by pH-dependent LysoTracker DND-99 fluorescence assay
Inhibition of recombinant human HDAC8 using H2N-Arg- His-Lys(Ac)-Lys(Ac)-AMC as substrate incubated for 90 mins and measured after 20 mins by fluorescence assay
Assay data:12 Active, 5 Activity ≤ 1 µM, 14 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of recombinant human HDAC6 using ZMAL (Z-(Ac)Lys-AMC as substrate incubated for 20 mins and measured by homogenous fluorescence assay
Assay data:11 Active, 6 Activity ≤ 1 µM, 14 Tested
Inhibition of recombinant human HDAC1 using ZMAL (Z-(Ac)Lys-AMC as substrate incubated for 20 mins and measured by homogenous fluorescence assay
Assay data:4 Active, 1 Activity ≤ 1 µM, 7 Tested
Inhibition of zebra fish HDAC10 using Ac-spermidine-AMC as substrate incubated for 25 mins and measured by fluorescence assay
Assay data:13 Active, 13 Activity ≤ 1 µM, 13 Tested
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on