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Inhibition of MMP2 mRNA expression in human H1299 cells at 3 uM after 48 hrs by RT-PCR analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed Citation
Inhibition of MMP9 mRNA expression in human H1299 cells at 3 uM after 48 hrs by RT-PCR analysis
Inhibition of MMP2 activity in human H1299 cells at 3 uM after 48 hrs by gelatin zymography
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of MMP9 activity in human H1299 cells at 3 uM after 48 hrs by gelatin zymography
Inhibition of cell invasion in human H1299 cells at 1 to 3 uM after 24 hrs by Boyden's chamber transwell invasion assay
Antimigratory activity in human H1299 cells at 1 to 6 uM incubated for 24 hrs by wound healing assay
Inhibition of beta-catenin signalling in human A549 cells assessed as reduction in beta-catenin level at 3 to 9 uM after 24 hrs by Western blot analysis
Inhibition of FAK phosphorylation in human A549 cells at 3 to 9 uM after 24 hrs by Western blot analysis
Inhibition of c-Src phosphorylation in human A549 cells at 3 to 9 uM after 24 hrs by Western blot analysis
Inhibition of JNK phosphorylation in human A549 cells at 3 to 9 uM after 24 hrs by Western blot analysis
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of p38 phosphorylation in human A549 cells at 3 to 9 uM after 24 hrs by Western blot analysis
Inhibition of ERK1/2 phosphorylation in human A549 cells after 24 hrs by Western blot analysis
Inhibition of MMP9 mRNA expression in human A549 cells at 3 uM after 48 hrs by RT-PCR analysis
Inhibition of MMP2 mRNA expression in human A549 cells at 3 uM after 48 hrs by RT-PCR analysis
Inhibition of MMP9 activity in human A549 cells at 3 to 9 uM after 48 hrs by gelatin zymography
Inhibition of MMP2 activity in human A549 cells at 3 to 9 uM after 48 hrs by gelatin zymography
Inhibition of cell invasion in human A549 cells at 1 to 3 uM after 24 hrs by Boyden's chamber transwell invasion assay
Antimigratory activity in human A549 cells incubated for 24 hrs by wound healing assay
SummaryPubMed Citation
Cell cycle arrest in human A549 cells assessed as accumulation at G2/M phase at 9 uM after 24 hrs by flow cytometry (Rvb = 15.1%)
Cell cycle arrest in human A549 cells assessed as accumulation at S phase at 9 uM after 24 hrs by flow cytometry (Rvb = 18.3%)
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