BioAssays for PubChem Compound (Select 24905401) - PubChem BioAssay - NCBI

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Select item 19531951.

Inhibition of SGK3 (unknown origin)

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Sgk3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1953195

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19531932.

Inhibition of AKT1 (unknown origin)

Source:: ChEMBL

Protein Target:: RAC-alpha serine/threonine-protein kinase

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1953193

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19531923.

Inhibition of p70S6K (unknown origin)

Source:: ChEMBL

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1953192

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19531914.

Inhibition of AKT2 (unknown origin)

Source:: ChEMBL

Protein Target:: RAC-beta serine/threonine-protein kinase

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1953191

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19531905.

Inhibition of RSK1 (unknown origin)

Source:: ChEMBL

Protein Target:: Ribosomal protein S6 kinase alpha-1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1953190

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19531896.

Inhibition of AKT3 (unknown origin)

Source:: ChEMBL

Protein Target:: RAC-gamma serine/threonine-protein kinase

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1953189

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19531737.

Inhibition of PKA (unknown origin)

Source:: ChEMBL

Protein Targets:: cAMP-dependent protein kinase catalytic subunit alpha; ...
Total:: 3

Assay data:8 Active, 2 Activity ≤ 1 µM, 11 Tested

AID:: 1953173

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19531648.

Inhibition of ROCK1 (unknown origin)

Source:: ChEMBL

Protein Target:: Rho-associated protein kinase 1

Assay data:5 Active, 1 Activity ≤ 1 nM, 5 Activity ≤ 1 µM, 6 Tested

AID:: 1953164

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19531629.

Inhibition of ROCK2 (unknown origin)

Source:: ChEMBL

Protein Target:: Rho-associated protein kinase 2

Assay data:21 Active, 5 Activity ≤ 1 nM, 21 Activity ≤ 1 µM, 21 Tested

AID:: 1953162

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 184522310.

Primary redox qHTS assay for identification of artifact compounds.

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:19 Active, 16 Activity ≤ 1 µM, 5098 Tested

AID:: 1845223

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor

Select item 184522211.

Primary Nanoluciferase (NLuc) qHTS assay for identification of artifact compounds.

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:37 Active, 2 Activity ≤ 1 µM, 5098 Tested

AID:: 1845222

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor

Select item 184522112.

Primary fluorescence-based thiol-reactive (MSTI) qHTS assay for identification of artifact compounds.

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:494 Active, 184 Activity ≤ 1 µM, 5098 Tested

AID:: 1845221

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor

Select item 184522013.

Primary firefly luciferase (FLuc) qHTS assay for identification of artifact compounds.

Source:: National Center for Advancing Translational Sciences (NCATS)

Protein Target:: Luciferin 4-monooxygenase

Assay data:75 Active, 14 Activity ≤ 1 µM, 5098 Tested

AID:: 1845220

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor

Select item 184519214.

Primary qHTS Assay for Inhibitors of Recombinant Selenoprotein Glutathione Peroxidase 4 (GPX4)

Source:: National Center for Advancing Translational Sciences (NCATS)

Protein Target:: Phospholipid hydroperoxide glutathione peroxidase

Assay data:258 Active, 16 Activity ≤ 1 µM, 11046 Tested

AID:: 1845192

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor Related BioAssays by Target

Select item 184519115.

Primary qHTS Assay for Inhibitors of Recombinant Selenoprotein Glutathione Peroxidase 1 (GPX1)

Source:: National Center for Advancing Translational Sciences (NCATS)

Protein Target:: Glutathione peroxidase 1

Assay data:186 Active, 9 Activity ≤ 1 µM, 11353 Tested

AID:: 1845191

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor Related BioAssays by Target

Select item 179480016.

NCI human tumor cell line growth inhibition assay. Data for the KM12 Non-Small Cell Lung cell line, single concentration

Source:: DTP/NCI

Assay data:3444 Active, 76734 Tested

AID:: 1794800

Summary Compounds, Active Related BioAssays by Depositor

Select item 179479917.

NCI human tumor cell line growth inhibition assay. Data for the HCC-2998 Non-Small Cell Lung cell line, single concentration

Source:: DTP/NCI

Assay data:3073 Active, 74254 Tested

AID:: 1794799

Summary Compounds, Active Related BioAssays by Depositor

Select item 179479818.

NCI human tumor cell line growth inhibition assay. Data for the HCT-116 Non-Small Cell Lung cell line, single concentration

Source:: DTP/NCI

Assay data:5131 Active, 77082 Tested

AID:: 1794798

Summary Compounds, Active Related BioAssays by Depositor

Select item 179479619.

NCI human tumor cell line growth inhibition assay. Data for the MCF7 Non-Small Cell Lung cell line, single concentration

Source:: DTP/NCI

Assay data:4318 Active, 77515 Tested

AID:: 1794796

Summary Compounds, Active Related BioAssays by Depositor

Select item 179479520.

NCI human tumor cell line growth inhibition assay. Data for the SW-620 Non-Small Cell Lung cell line, single concentration

Source:: DTP/NCI

Assay data:3653 Active, 76840 Tested

AID:: 1794795

Summary Compounds, Active Related BioAssays by Depositor

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Target

Proteins (12)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (434)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (42)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (286)
BioAssays with the active concentration of tested reagents less than 1 micromolar

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Confirmatory (384)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (58)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose

Assay Project (2)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (25)
BioAssays extracted from the literature
NIH MLP (21)
BioAssays deposited by the NIH Molecular Libraries Program
Other (414)
BioAssays deposited by other experimentalists

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