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Cytotoxicity activity against human HepG2 cells assessed by CellTiter-Glo luminescent cell viability assay.
Assay data:1241 Active, 184 Activity ≤ 1 µM, 1545 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µM
Induction of apoptosis in human CD4+ve Th cells
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed Citation
Induction of Ahr nuclear translocation in human HaCaT cells assessed as decrease in Ahr in nucleus at 10 uM incubated for 1 hr by Western blot analysis
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Agonist activity at AhR in human recombinant HepG2-Lucia AhR cell incubated for 24 hrs by luciferase reporter gene assay
Assay data:28 Active, 5 Activity ≤ 1 nM, 21 Activity ≤ 1 µM, 39 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of Hedgehog-signalling dependent purmorphamine induced osteoblast differentiation in mouse C3H 10T1/2 cells assessed as reduction in ALP expression at 0.01 to 100 uM incubated for 96 hrs by CDP-Star luminogenic substrate based assay
Assay data:6 Active, 6 Tested
Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging
Assay data:7212 Tested
Summary
SARS-CoV-2 3CL-Pro protease inhibition percentage at 20 M by FRET kind of response from peptide substrate
SummaryRelated BioAssays by Target
Antimicrobial activity against Bacillus subtilis NCIB3610 assessed as inhibition of microbial growth at 50 ug/disk incubated at 30 degC for 24 hrs by paper disk method
SummaryPubMed Citation
Antimicrobial activity against Escherichia coli Nissle1917 assessed as inhibition of microbial growth incubated at 30 degC for 24 hrs by paper disk method
Antimicrobial activity against Saccharomyces cerevisiae assessed as inhibition of microbial growth at 50 ug/disk incubated at 30 degC for 24 hrs by paper disk method
Assay data:1 Active, 2 Tested
Nematicidal activity against J4 juvenile of Caenorhabditis elegans after 24 hr
Assay data:1 Tested
Nematicidal activity against adult Caenorhabditis elegans after 24 hr
Induction of virulence of stlA deficient Photorhabdus luminescens BMM901 assessed as increase in proliferation of Photorhabdus luminescens BMM901 in Manduca sexta in presence of cinnamic acid
Induction of virulence of stlA deficient Photorhabdus luminescens BMM901 assessed as decrease in survival of Photorhabdus luminescens BMM901 infected Manduca sexta in presence of cinnamic acid
Induction of virulence of Photorhabdus luminescens TT01 assessed as increase in proliferation of Photorhabdus luminescens TT01 in Manduca sexta in presence of cinnamic acid
Induction of virulence of Photorhabdus luminescens TT01 assessed as decrease in survival of Photorhabdus luminescens TT01 infected Manduca sexta in presence of cinnamic acid
Drug level in Photorhabdus luminescens TT01 infected Manduca sexta hemolymph after 24 hrs by TLC plate method
Induction of virulence of Photorhabdus luminescens TT01 assessed as increase in proliferation of Photorhabdus luminescens TT01 in Manduca sexta
Induction of virulence of Photorhabdus luminescens TT01 assessed as decrease in survival of Photorhabdus luminescens TT01 infected Manduca sexta
Inhibition of immune system assessed as suppression of melanotic nodule formation in Photorhabdus luminescens TT01 infected Manduca sexta
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